Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Cluster miRNAs and cancer: Diagnostic, prognostic and therapeutic opportunities

SP Kabekkodu, V Shukla, VK Varghese… - Wiley …, 2020 - Wiley Online Library
MiRNAs are class of noncoding RNA important for gene expression regulation in many
plants, animals and viruses. MiRNA clusters contain a set of two or more miRNA encoding …

[HTML][HTML] MicroRNAs: molecular features and role in cancer

E Lages, H Ipas, A Guttin, H Nesr, F Berger… - Frontiers in …, 2012 - ncbi.nlm.nih.gov
Abstract microRNAs (miRNAs) are small noncoding endogenously produced RNAs that play
key roles in controlling the expression of many cellular proteins. Once they are recruited and …

Biological functions of microRNAs: a review

Y Huang, XJ Shen, Q Zou, SP Wang, SM Tang… - Journal of physiology …, 2011 - Springer
MicroRNAs (miRNAs) are a recently discovered family of endogenous, noncoding RNA
molecules approximately 22 nt in length. miRNAs modulate gene expression post …

Interplay between miRNAs and host genes and their role in cancer

B Liu, Y Shyr, J Cai, Q Liu - Briefings in functional genomics, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs that post-
transcriptionally regulate gene expression. They play essential roles in nearly all biological …

MicroRNAs–micro in size but macro in function

SK Singh, M Pal Bhadra, HJ Girschick… - The FEBS …, 2008 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous small RNAs that can regulate target mRNAs by
binding to their 3′‐UTRs. A single miRNA can regulate many mRNA targets, and several …

Human microRNA clusters: genomic organization and expression profile in leukemia cell lines

J Yu, F Wang, GH Yang, FL Wang, YN Ma… - Biochemical and …, 2006 - Elsevier
MicroRNAs (miRNAs) play an important role in diverse physiological and developmental
processes by negatively regulating expression of target genes at the post-transcriptional …

MicroRNAs in cancer

G Di Leva, M Garofalo, CM Croce - Annual Review of Pathology …, 2014 - annualreviews.org
MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such …

[HTML][HTML] The role of MicroRNAs in human cancer

Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

[HTML][HTML] MicroRNAs: critical mediators of differentiation, development and disease

JM Friedman, PA Jones - Swiss medical weekly, 2009 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that are expressed in higher eukaryoates
and have even been found in viral genomes. They usually act as endogenous repressors of …