Oral delivery of drugs with poor aqueous solubility and poor enzymatic and/or metabolic
stability is very challenging. However, the advent of nanotechnology has revolutionized the …

The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …

The field of nanomedicine offers promising new drug delivery systems with enhanced
properties. The literature has reported on the development of various nanomedicines that …

An increasing percentage of drug development candidates suffer from poor aqueous
solubility which in turn often times leads to poor oral absorption. This poses significant …

The increasing frequency at which poorly soluble new chemical entities are being
discovered raises concerns in the pharmaceutical industry about drugability associated with …

Rapid advancement in drug discovery process is leading to a number of potential new drug
candidates having excellent drug efficacy but limited aqueous solubility. By virtue of the …

Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …

Nanotechnology as a delivery platform offers very promising applications in drug delivery,
especially through and for the oral route. Either direct nanosizing or incorporation into …

Nanotechnology ushered the field of medicine in to a new era. Miniaturization, increased
surface area, and the unique physicochemical properties in the nano dimension were …

Bioavailability is an eternal topic that cannot be circumvented by peroral drug delivery.
Adequate blood drug exposure after oral administration is a prerequisite for effective …