Cancer stem cells (CSCs) are subpopulation of cells which have been demonstrated in a
variety of cancer models and involved in cancer initiation, progression, and development …

The process of cancer development and progression is driven by distinct subsets of cancer
stem cells (CSCs) that contribute the self-renewal capacity as the major impetus to the …

Molecular docking in the pharmaceutical industry is a powerful in silico approach for
discovering novel therapies for unmet medical needs predicting drug–target interactions. It …

Diclofenac is a potent NSAID of clinical choice, which is widely used for containing
inflammation. Moreover, recent experimental evidences overwhelmingly substantiate its …

The subpopulation of cancer stem cells (CSCs) within tumor bulk are known for tumor
recurrence and metastasis. CSCs show intrinsic resistance to conventional therapies and …

Background: Cancer is a leading risk of death globally. According to the World Health
Organization, it is presently the second most important disease that causes death in both …

Cancer heterogeneity constitutes the major source of disease progression and therapy
failure. Tumors comprise functionally diverse subpopulations, with cancer stem cells (CSCs) …

Phenotypic and functional heterogeneity is one of the most relevant features of cancer cells
within different tumor types and is responsible for treatment failure. Cancer stem cells …

It is well known that cancer cells are heterogeneous in nature and very distinct from their
normal counterparts. Commonly these cancer cells possess different and complementary …

Most human tumors possess a high heterogeneity resulting from both clonal evolution and
cell differentiation program. The process of cell differentiation is initiated from a population of …