Terpenoids' anti-cancer effects: Focus on autophagy

C El-Baba, A Baassiri, G Kiriako, B Dia, S Fadlallah… - Apoptosis, 2021 - Springer
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …

Monoterpenes modulating autophagy: A review study

M Ashrafizadeh, Z Ahmadi… - Basic & Clinical …, 2020 - Wiley Online Library
From the beginning of the 21st century, much attention has been made towards the
medicinal herbs due to their low side effects and valuable biological activities. Among them …

Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy

SR Lin, YS Fu, MJ Tsai, H Cheng, CF Weng - International Journal of …, 2017 - mdpi.com
Accumulated evidence indicates that autophagy is a response of cancer cells to various anti-
cancer therapies. Autophagy is designated as programmed cell death type II, and is …

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

N Hasima, B Ozpolat - Cell death & disease, 2014 - nature.com
Autophagy, a lysosomal degradation pathway for cellular constituents and organelles, is an
adaptive and essential process required for cellular homeostasis. Although autophagy …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells

C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …

Phytochemicals as a complement to cancer chemotherapy: pharmacological modulation of the autophagy-apoptosis pathway

MA Rahman, MA Hannan, R Dash… - Frontiers in …, 2021 - frontiersin.org
Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …

Apoptosis and autophagy modulating dietary phytochemicals in cancer therapeutics: Current evidences and future perspectives

S Patra, B Pradhan, R Nayak, C Behera… - Phytotherapy …, 2021 - Wiley Online Library
The global incidence of cancer and cancer‐related mortality is expected to rise in recent
years despite advancements in cancer diagnosis and therapeutics. Increasing evidences of …

Modulation of autophagy in cancer cells by dietary polyphenols

C Musial, K Siedlecka-Kroplewska, Z Kmiec… - Antioxidants, 2021 - mdpi.com
The role of autophagy is to degrade damaged or unnecessary cellular structures. Both in
vivo and in vitro studies suggest a dual role of autophagy in cancer—it may promote the …

Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agents

X Zhang, LX Chen, L Ouyang, Y Cheng… - Cell proliferation, 2012 - Wiley Online Library
Natural compounds derived from plant sources are well characterized as possessing a wide
variety of remarkable anti‐tumour properties, for example modulating programmed cell …