Obesity as a Condition determined by Food Addiction: should Brain Endocannabinoid System alterations be the cause and its Modulation the Solution?

M de Ceglia, J Decara, S Gaetani… - Pharmaceuticals, 2021 - mdpi.com
Obesity is a complex disorder, and the number of people affected is growing every day. In
recent years, research has confirmed the hypothesis that food addiction is a determining …

The role of the endocannabinoid system in eating disorders: pharmacological implications

EM Marco, SY Romero-Zerbo, MP Viveros… - Behavioural …, 2012 - journals.lww.com
The endocannabinoid (eCB) system is a widespread intercellular signalling mechanism that
plays a critical role in body homoeostasis. It is located in key points involved in food intake …

The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning?

FJ Bermudez-Silva, MP Viveros, JM McPartland… - Pharmacology …, 2010 - Elsevier
The endocannabinoid system (ECS) consists of two receptors (CB1 and CB2), several
endogenous ligands (primarily anandamide and 2-AG), and over a dozen ligand …

Endocannabinoids and metabolic disorders

B Gatta-Cherifi, D Cota - Endocannabinoids, 2015 - Springer
The endocannabinoid system (ECS) is known to exert regulatory control on essentially every
aspect related to the search for, and the intake, metabolism and storage of calories, and …

Energy balance regulation by endocannabinoids at central and peripheral levels

C Quarta, R Mazza, S Obici, R Pasquali… - Trends in molecular …, 2011 - cell.com
Dysregulation of the endocannabinoid system (ECS) is a universal and, perhaps, causative
feature of obesity. Central nervous system (CNS) circuits that regulate food intake were …

The unfolding cannabinoid story on energy homeostasis: central or peripheral site of action?

TL Horvath - International journal of Obesity, 2006 - nature.com
Presentations in this symposium addressed effects and modes of action of
endocannabinoids in various tissues in relation to metabolic disorders. Endocannabinoids …

The role of the endocannabinoid system in eating disorders: neurochemical and behavioural preclinical evidence

M Scherma, L Fattore, M Paola Castelli… - Current …, 2014 - ingentaconnect.com
The endocannabinoid system has long been known as a modulator of several physiological
functions, among which the homeostatic and hedonic aspects of eating. CB1 receptors are …

Role of the endocannabinoid system in energy balance regulation and obesity

D Cota - Obesity and Metabolism, 2008 - karger.com
The endogenous cannabinoid system (ECS) is a neuromodulatory system recently
recognized to have a role in the regulation of various aspects of eating behavior and energy …

The endocannabinoid system and the treatment of obesity

U Pagotto, V Vicennati, R Pasquali - Annals of medicine, 2005 - Taylor & Francis
The endocannabinoids are endogenous lipids capable of binding to both cannabinoid
receptors (CB) CB1 and CB2. These receptors belong to the G protein–coupled family …

Endocannabinoid signaling and food addiction

C D'Addario, MVM Di Bonaventura, M Pucci… - Neuroscience & …, 2014 - Elsevier
Overeating, frequently linked to an increasing incidence of overweight and obesity, has
become epidemic and one of the leading global health problems. To explain the …