Circadian rhythm analysis using wearable-based accelerometry as a digital biomarker of aging and healthspan

J Shim, E Fleisch, F Barata - npj Digital Medicine, 2024 - nature.com
Recognizing the pivotal role of circadian rhythm in the human aging process and its
scalability through wearables, we introduce CosinorAge, a digital biomarker of aging …

Wearable-based accelerometer activity profile as digital biomarker of inflammation, biological age, and mortality using hierarchical clustering analysis in NHANES …

J Shim, E Fleisch, F Barata - Scientific Reports, 2023 - nature.com
Repeated disruptions in circadian rhythms are associated with implications for health
outcomes and longevity. The utilization of wearable devices in quantifying circadian rhythm …

[PDF][PDF] Wearable-based physical activity as a digital biomarker of inflammation, biological age, and mortality: a hierarchical clustering analysis of NHANES 2011-2014 …

J Shim, E Fleisch, F Barata - 2023 - scholar.archive.org
Current measures of health and longevity are based on factors such as in ammation,
biological age, and mortality. The potential of using continuously collected data from digital …

Comparative efficacy of commercial wearables for circadian rhythm home monitoring from activity, heart rate, and core body temperature

F Wu, P Langer, J Shim, E Fleisch, F Barata - arXiv preprint arXiv …, 2024 - arxiv.org
Circadian rhythms govern biological patterns that follow a 24-hour cycle. Dysfunctions in
circadian rhythms can contribute to various health problems, such as sleep disorders …

Blunted rest–activity circadian rhythm is associated with increased rate of biological aging: an analysis of NHANES 2011–2014

Y Xu, X Wang, DW Belsky, WV McCall… - The Journals of …, 2023 - academic.oup.com
Impaired rest–activity circadian rhythm has been associated with increased risk for morbidity
and mortality. Animals with mutations in clock genes display accelerated aging and …

Biological age prediction from wearable device movement data identifies nutritional and pharmacological interventions for healthy aging

RL McIntyre, M Rahman, SA Vanapalli… - Frontiers in …, 2021 - frontiersin.org
Intervening in aging processes is hypothesized to extend healthy years of life and treat age-
related disease, thereby providing great benefit to society. However, the ability to measure …

Circadian monitoring as an aging predictor

A Martinez-Nicolas, JA Madrid, FJ García, M Campos… - Scientific reports, 2018 - nature.com
The ageing process is associated with sleep and circadian rhythm (SCR) frailty, as well as
greater sensitivity to chronodisruption. This is essentially due to reduced day/night contrast …

Distinct circadian assessments from wearable data reveal social distancing promoted internal desynchrony between circadian markers

Y Huang, C Mayer, OJ Walch, C Bowman… - Frontiers in Digital …, 2021 - frontiersin.org
Mobile measures of human circadian rhythms (CR) are needed in the age of chronotherapy.
Two wearable measures of CR have recently been validated: one that uses heart rate to …

circadian rhythms are not captured equal: Exploring Circadian metrics extracted by differentcomputational methods from smartphone accelerometer and GPS sensors …

C Wu, M McMahon, H Fritz, DM Schnyer - Digital Health, 2022 - journals.sagepub.com
Objective To identify the differences between circadian rhythm (CR) metrics characterized by
different mobile sensors and computational methods. Methods We used smartphone …

Phenome-wide association study of actigraphy in the UK Biobank

TG Brooks, NF Lahens, GR Grant, YI Sheline… - MedRxiv, 2021 - medrxiv.org
Wrist-worn accelerometer actigraphy devices present the opportunity for large-scale data
collection from people during their daily lives. Using data from approximately 100,000 …