Tumor microenvironment and immune response in lip cancer

AG Gkegka, MI Koukourakis, M Lambropoulou… - Cancers, 2023 - mdpi.com
Simple Summary The presence of tumor-infiltrating lymphocytes (TILs) in the tumor milieu
has been linked to better patient prognosis and response to chemo-radiotherapy in head …

Cancer Microenvironment defines tumor-infiltrating lymphocyte density and tertiary lymphoid structure formation in Laryngeal Cancer

AG Gkegka, MI Koukourakis, M Katotomichelakis… - Head and Neck …, 2023 - Springer
Background The presence and activity of tumor-infiltrating lymphocytes (TILs) is a key
parameter related to the antitumor immune response. A large number of studies reveal TIL …

The repertoire of tumor-infiltrating lymphocytes within the microenvironment of oral squamous cell carcinoma reveals immune dysfunction

H Quan, Z Shan, Z Liu, S Liu, L Yang, X Fang… - Cancer Immunology …, 2020 - Springer
Background The role of tumor-infiltrating lymphocytes (TILs) in the immune remodeling of
tumor microenvironments (TME) in oral squamous cell carcinoma (OSCC) remains …

[HTML][HTML] Expression of CD4+ and CD8+ Tumor-Infiltrating Lymphocytes in Oral Squamous Cell Carcinoma and Their Relationship With Clinicopathological Parameters …

SM Jeyapriya, AM Mohan, MS Kumar, RM Nirmal - Cureus, 2024 - ncbi.nlm.nih.gov
Background Oral squamous cell carcinoma (OSCC) is the most common malignant
neoplasm of the oral cavity. The tumor microenvironment (TME) is a dynamic ecosystem …

Prognostic and predictive relevance of tumor-infiltrating lymphocytes in squamous cell head–neck cancer patients treated with radical Radiotherapy/Chemo …

IM Koukourakis, AG Gkegka, E Xanthopoulou… - Current …, 2022 - mdpi.com
Microenvironmental conditions control the entrance and thriving of cytotoxic lymphocytes in
tumors, allowing or preventing immune-mediated cancer cell death. We investigated the role …

Tumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer

P Balermpas, F Rödel, C Weiss, C Rödel… - …, 2014 - Taylor & Francis
Tumor-infiltrating lymphocytes (TILs) play an important role in the response of neoplastic
lesions to therapy. We have recently shown that a robust tumor infiltration by CD3+ and …

The prognostic role of tumor infiltrating T-lymphocytes in squamous cell carcinoma of the head and neck: A systematic review and meta-analysis

EJ de Ruiter, ML Ooft, LA Devriese… - Oncoimmunology, 2017 - Taylor & Francis
Background–The presence of tumor-infiltrating lymphocytes (TILs) in the tumor
microenvironment is associated with an improved prognosis and a better response to …

Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma

N Nguyen, E Bellile, D Thomas, J McHugh… - Head & …, 2016 - Wiley Online Library
Background Because immune responses within the tumor microenvironment are important
predictors of tumor biology, correlations of types of tumor infiltrating lymphocytes (TILs) with …

Prognostic significance of CD4+ and CD8+ tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma: a meta-analysis

D Borsetto, M Tomasoni, K Payne, J Polesel… - Cancers, 2021 - mdpi.com
Simple Summary Tumor infiltrating lymphocytes (TILs) have been demonstrated as
prognostic biomarkers in multiple cancer types. Among the various TIL phenotypic sub …

Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+B-cells in metastatic lymph nodes are associated with favourable outcome in patients …

D Pretscher, LV Distel, GG Grabenbauer, M Wittlinger… - BMC cancer, 2009 - Springer
Background Tumour infiltrating lymphocytes (TIL) are generally considered to represent a
host immune response directed against tumour antigens. TIL are also increasingly …