A critical overview of computational approaches employed for COVID-19 drug discovery
COVID-19 has resulted in huge numbers of infections and deaths worldwide and brought
the most severe disruptions to societies and economies since the Great Depression …
the most severe disruptions to societies and economies since the Great Depression …
Therapeutics for COVID-19: from computation to practices—where we are, where we are heading to
Abstract After the 1918 Spanish Flu pandemic caused by the H1N1 virus, the recent
coronavirus disease 2019 (COVID-19) brought us to the time of serious global health …
coronavirus disease 2019 (COVID-19) brought us to the time of serious global health …
Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review
K Mohamed, N Yazdanpanah, A Saghazadeh… - Bioorganic …, 2021 - Elsevier
Background Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak,
there has been an increasing interest in finding a potential therapeutic agent for the disease …
there has been an increasing interest in finding a potential therapeutic agent for the disease …
Advances in the computational landscape for repurposed drugs against COVID-19
I Aronskyy, Y Masoudi-Sobhanzadeh, A Cappuccio… - Drug Discovery …, 2021 - Elsevier
The COVID-19 pandemic has caused millions of deaths and massive societal distress
worldwide. Therapeutic solutions are urgently needed, but de novo drug development …
worldwide. Therapeutic solutions are urgently needed, but de novo drug development …
[HTML][HTML] Boosting the arsenal against COVID-19 through computational drug repurposing
G Ciliberto, L Cardone - Drug discovery today, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) world health emergency is calling scientists for
unprecedented, huge investigation efforts to urgently answer key questions: what is the …
unprecedented, huge investigation efforts to urgently answer key questions: what is the …
Quest for a COVID-19 cure by repurposing small-molecule drugs: mechanism of action, clinical development, synthesis at scale, and outlook for supply
C De Savi, DL Hughes, L Kvaerno - Organic Process Research & …, 2020 - ACS Publications
The outbreak of the COVID-19 pandemic has spurred an intense global effort to repurpose
existing approved drugs for its treatment. In this review, we highlight the development of …
existing approved drugs for its treatment. In this review, we highlight the development of …
A comprehensive review of drug repurposing strategies against known drug targets of COVID-19
Drug repurposing is a more inexpensive and shorter approach than the traditional drug
discovery and development process. The concept of identifying a potent molecule from a …
discovery and development process. The concept of identifying a potent molecule from a …
COVID‐19 drug repurposing: a review of computational screening methods, clinical trials, and protein interaction assays
X Wang, Y Guan - Medicinal research reviews, 2021 - Wiley Online Library
The situation of coronavirus disease 2019 (COVID‐19) pandemic is rapidly evolving, and
medical researchers around the globe are dedicated to finding cures for the disease. Drug …
medical researchers around the globe are dedicated to finding cures for the disease. Drug …
Drug targets for COVID-19 therapeutics: Ongoing global efforts
A Saxena - Journal of biosciences, 2020 - Springer
The current global pandemic COVID-19 caused by the SARS-CoV-2 virus has already
inflicted insurmountable damage both to the human lives and global economy. There is an …
inflicted insurmountable damage both to the human lives and global economy. There is an …
COVID-19 drug discovery using intensive approaches
A Asai, M Konno, M Ozaki, C Otsuka… - International journal of …, 2020 - mdpi.com
Since the infectious disease caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was reported in China during December 2019, the coronavirus disease 2019 …
(SARS-CoV-2) was reported in China during December 2019, the coronavirus disease 2019 …