Breast cancer is the most common neoplastic disease in women worldwide. Development of
breast cancer is profoundly influenced by prolonged exposure to estrogens, but the role of …

Estrogens play a crucial role in the development and evolution of human breast cancer.
However, it is still unclear whether estrogens are carcinogenic to the human breast. There …

Many studies have reported a correlation between elevated estrogen blood levels and
breast cancer, and this observation has raised controversy concerning the long-term use of …

In female mammals, the development and regulation of the reproductive system and non-
reproductive system are significantly influenced by estrogens (oestrogens). In addition, lipid …

Long term exposure to estrogens is associated with an increased risk of breast cancer. The
precise mechanisms responsible for estrogen mediated carcinogenesis are not well …

A female hormone, estrogen, is linked to breast cancer incidence. Estrogens undergo phase
I and II metabolism by which they are biotransformed into genotoxic catechol estrogen …

Despite the dramatic fall in plasma estrogen levels at menopause, only minor differences in
breast tissue estrogen levels have been reported comparing pre-and postmenopausal …

Estrogen Carcinogenesis in Breast Cancer | NEJM Skip to main content NEJM Group Follow Us
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A common thread linking the main risks for developing breast cancer in women is
cumulative, excessive exposure to estrogen. The standard paradigm to account for this …

SY14-1 Even though the breast is influenced by a myriad of hormones and growth factors,
estrogens are considered to play a major role in promoting the proliferation of both the …