A road map for understanding molecular and genetic determinants of osteoporosis
Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
Osteoporosis and bone mass disorders: from gene pathways to treatments
F Rivadeneira, O Mäkitie - Trends in Endocrinology & Metabolism, 2016 - cell.com
Genomic technologies have evolved rapidly contributing to the understanding of diseases.
Genome-wide association studies (GWAS) and whole-exome sequencing have aided the …
Genome-wide association studies (GWAS) and whole-exome sequencing have aided the …
Genetics of osteoporosis from genome-wide association studies: advances and challenges
Osteoporosis is among the most common and costly diseases and is increasing in
prevalence owing to the ageing of our global population. Clinically defined largely through …
prevalence owing to the ageing of our global population. Clinically defined largely through …
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density
Aiming to identify novel genetic variants and to confirm previously identified genetic variants
associated with bone mineral density (BMD), we conducted a three-stage genome-wide …
associated with bone mineral density (BMD), we conducted a three-stage genome-wide …
Genetics of osteoporosis
QY Huang, AWC Kung - Molecular Genetics and Metabolism, 2006 - Elsevier
Osteoporosis is a common disease with a strong genetic component. In recent years, some
progress has been made in understanding the genetic basis of osteoporosis. Genetic factors …
progress has been made in understanding the genetic basis of osteoporosis. Genetic factors …
Molecular genetic studies of gene identification for osteoporosis: the 2009 update
XH Xu, SS Dong, Y Guo, TL Yang, SF Lei… - Endocrine …, 2010 - academic.oup.com
Osteoporosis is a complex human disease that results in increased susceptibility to fragility
fractures. It can be phenotypically characterized using several traits, including bone mineral …
fractures. It can be phenotypically characterized using several traits, including bone mineral …
Searching for osteoporosis genes in the post-genome era: progress and challenges
Osteoporosis is a common skeletal disease characterized by low bone mineral density
(BMD), deterioration of bone microarchitecture and increased fracture risk. It is a complex …
(BMD), deterioration of bone microarchitecture and increased fracture risk. It is a complex …
[HTML][HTML] An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related …
Osteoporosis is a complex disorder and commonly leads to fractures in elderly persons.
Genome-wide association studies (GWAS) have become an unbiased approach to identify …
Genome-wide association studies (GWAS) have become an unbiased approach to identify …
Novel insights into the complex architecture of osteoporosis molecular genetics
FA Saad - Annals of the New York Academy of Sciences, 2020 - Wiley Online Library
Osteoporosis is a prevalent osteodegenerative disease and silent killer linked to a decrease
in bone mass and decline of bone microarchitecture, due to impaired bone matrix …
in bone mass and decline of bone microarchitecture, due to impaired bone matrix …
Genetics of osteoporosis: accelerating pace in gene identification and validation
Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …