Objectives The present research focused on estimating, for the first time, the potential
protective effects of bromelain against D-galactosamine-induced acute liver injury in rats as …

Shikonin, a naphthoquinone isolated from the root of medical herb Lithospermum
erythrorhizon, has been reported to have anti-inflammatory effect. However, there is no …

OBJECTIVE: Acute liver injury (ALI) is mainly characterized by the symptom of metabolic
disorders, homeostasis unbalance, and loss of liver function. There are no effective …

Fulminant hepatic failure (FHF), associated with high mortality, is characterized by extensive
death of hepatocytes and hepatic dysfunction. There is no effective treatment for FHF …

Acute liver injury (ALI) is a life-threatening syndrome accompanied by overwhelming
inflammation. Amygdalin (AGD) has been reported to possess various biological activities …

Objectives Aimed to investigate the effect and mechanism of methyl 3, 4-dihydroxybenzoate
(MDHB) on d-galactosamine/lipopolysaccharide (d-galN/LPS)-induced acute liver failure …

The purpose of this study was to synthesize 4-hydroxybenzo [d] oxazol-2 (3H)-one (HBO)
and to investigate its protective effects on lipopolysaccharide (LPS)/D-galactosamine (D …

The prognosis for fulminant hepatic failure (FHF) still remains extremely poor with a high
mortality and, therefore, better treatments are urgently needed. Syringin, a main active …

The hepatoprotective effects and molecular mechanisms of baicalein on acute liver failure
induced by d-galactosamine (d-GalN)/lipopolysaccharides (LPS) were investigated in vivo …

Methods Mice were pretreated with ginsenoside Rb1 by intraperitoneal injection for 3 days
before D-GalN/LPS treatment, to induce ALI. The survival rate was monitored every hour for …