[HTML][HTML] Advances in oral drug delivery

MS Alqahtani, M Kazi, MA Alsenaidy… - Frontiers in …, 2021 - frontiersin.org
The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …

Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems

Y Xu, N Shrestha, V Préat, A Beloqui - Journal of controlled release, 2020 - Elsevier
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …

Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers

JP Gleeson, SM Ryan, DJ Brayden - Trends in Food Science & Technology, 2016 - Elsevier
Background Lifestyle issues contribute to the development of obesity, type 2 diabetes, and
cardiovascular disease. Together with appropriate diet and exercise, nutraceuticals may …

Diverse approaches for the enhancement of oral drug bioavailability

P Fasinu, V Pillay, VMK Ndesendo… - … & drug disposition, 2011 - Wiley Online Library
In conscious and co‐operating patients, oral drug delivery remains the preferable route of
drug administration. However, not all drugs possess the desirable physicochemical and …

[HTML][HTML] Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery

M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …

Bioavailability enhancement strategies: basics, formulation approaches and regulatory considerations

S Beg, S Swain, M Rizwan, M Irfanuddin… - Current Drug …, 2011 - ingentaconnect.com
Poor solubility remains a major challenge for pharmaceutical industry, which is now
considered to be an area of prime importance in the field of biomedical research …

[HTML][HTML] Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

Oral transmucosal drug delivery for pediatric use

JKW Lam, Y Xu, A Worsley, ICK Wong - Advanced drug delivery reviews, 2014 - Elsevier
The formulation of medicines for children remains a challenge. An ideal pediatric formulation
must allow accurate dose administration and be in a dosage form that can be handled by the …

Oral absorption basics: pathways and physicochemical and biological factors affecting absorption

L Zhu, L Lu, S Wang, J Wu, J Shi, T Yan, C Xie… - Developing solid oral …, 2017 - Elsevier
To be effective, drugs in an oral dosage form first must be absorbed and then reach the
target organs via systemic circulation. Barriers that prevent drugs from reaching the systemic …