Despite the great progress made in setting the basis for the molecular diversity of
acetylcholinesterase (AChE), an explanation for the existence of two types of amphiphilic …

The observation of acetylcholinesterase (AChE) type H (AChEH), which is the predominant
AChE variant in visceral organs and immune cells, in lipid rafts of muscle supports functional …

Cholesterol-sphingolipid microdomains, or lipid rafts, are major regulators of molecular
interactions in membrane organization. Because lipid rafts can move laterally and cluster …

Emerging concepts of membrane organization point to the compartmentalization of the
plasma membrane into distinct lipid microdomains. This lateral segregation within cellular …

Background information. Cholesterol/sphingolipid‐rich membrane microdomains or
membrane rafts have been implicated in various aspects of receptor function such as …

The collagen-tailed form of acetylcholinesterase (ColQ-AChE) is the major if not unique form
of the enzyme associated with the specialized synaptic basal lamina at the neuromuscular …

Motor innervation of the skeletal muscle leads to the clustering of acetylcholine receptor
(AChR) in the postsynaptic membrane. It was hypothesized that the establishment of a …

Agrin, a motoneuron-derived factor, and the muscle-specific receptor tyrosine kinase (MuSK)
are essential for the acetylcholine receptor (AChR) clustering at the postjunctional …

A glycolipid anchorage for acetylcholinesterase (AChE) has been found in some tissues. In
this paper, the possibility of such an anchorage has been explored in mammalian muscle …

Cholesterol is an essential partner of the nicotinic acetylcholine receptor (AChR). It is not
only an abundant component of the postsynaptic membrane but also affects the stability of …