The protein kinase inhibitor Staurosporine was found to be a potent relaxant of rabbit aortic
strips contracted by various agonists. This relaxing effect was slow, long-lasting and in a non …

We examined the effects of staurosporine, a protein kinase inhibitor, on Ca2+ movements
and contractions due to KCl and 12-deoxyphorbol 13-isobutyrate (DPB), which are thought …

1 Inhibitory effects of a novel smooth muscle relaxant, KT‐362 (5‐[3‐([2‐(3, 4‐
dimethoxyphenyl)‐ethyl] amino)‐1‐oxopropyl]‐2, 3, 4, 5‐tetrahydro‐1, 5‐benzothiazepine …

The effect of thapsigargin, a specific inhibitor of intracellular Ca 2+-ATPases, on
endothelium-dependent relaxation was studied in the guinea pig thoracic aorta …

Exposure of rabbit aortic strips to SKF 525A (2.6 x 10-5 M; 1 x 10-5 g/ml) for 30 minutes
blocked potassium-induced contractions without reducing those to moderate concentrations …

To elucidate the mechanism of contraction of the smooth muscle of the rat's aorta, its
response to norepinephrine (NE), 5-hydroxytrypatamine (5-HT) and potassium chloride …

Noradrenaline (NA) produces sustained contractions in conduit arteries such as aorta
isolated from various animal species. In guinea-pig aorta, NA-produced sustained …

The effects of daunorubicin on vasocontraction by several agonists have been investigated
on isolated aortic strips from rats. Pretreatment of the strips with daunorubicin (17.7 μM) …

In rat thoracic aorta, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) caused a slowly onset,
sustained vascular contraction. The contraction was markedly reduced in the absence of …

We assessed the specificity of staurosporine, a putative protein kinase C inhibitor, for the
enzyme in intact porcine coronary arteries by examining its effects on changes in …