Impairments of vision and hearing are highly prevalent conditions limiting the quality of life
and presenting a major socioeconomic burden. For a long time, retinal and cochlear …

Highlights•Optogenetic stimulation of the auditory pathway promises unprecedented
research opportunities and a fundamental advance for hearing restoration.•Feasibility and …

Cochlear implants (CI s) are considered the most successful neuroprosthesis as they enable
speech comprehension in the majority of half a million CI users suffering from sensorineural …

Recent advances in optogenetics hold promise for vision restoration in degenerative eye
diseases. Optogenetics refers to techniques that use light to control the cellular activity of …

Optogenetics is a recent breakthrough in neuroscience, and one of the most promising
applications is the treatment of retinal degenerative diseases. Multiple clinical trials are …

When hearing fails, cochlear implants (CIs) provide open speech perception to most of the
currently half a million CI users. CIs bypass the defective sensory organ and stimulate the …

Inherited retinal disease (IRD) affects about 1 in 3000 to 1 in 5000 individuals and is now
believed to be the most common cause of blindness registration in developed countries …

Optogenetic is a technique that combines optics and genetics to control specific neurons.
This technique usually uses adenoviruses that encode photosensitive protein. The …

Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in
basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this …

Degenerative retinal disorders are a diverse family of diseases commonly leading to
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …