[HTML][HTML] Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy

C Gong, J Tian, Z Wang, Y Gao, X Wu, X Ding… - Journal of …, 2019 - Springer
Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological
information between cells. However, Exo are limited in terms of their abilities to target …

Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer

H Nie, X Xie, D Zhang, Y Zhou, B Li, F Li, F Li, Y Cheng… - Nanoscale, 2020 - pubs.rsc.org
Engineered exosomes have become popular drug delivery carriers for cancer treatment.
This is partially due to the interesting property, ie exosome organotropism, which plays an …

Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells

G Liang, S Kan, Y Zhu, S Feng, W Feng… - International journal of …, 2018 - Taylor & Francis
Introduction Exosomes are closed-membrane nanovesicles that are secreted by a variety of
cells and exist in most body fluids. Recent studies have demonstrated the potential of …

[HTML][HTML] Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

S Ohno, M Takanashi, K Sudo, S Ueda, A Ishikawa… - Molecular therapy, 2013 - cell.com
Despite the therapeutic potential of nucleic acid drugs, their clinical application has been
limited in part by a lack of appropriate delivery systems. Exosomes or microvesicles are …

Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo

Z Naseri, RK Oskuee, MR Jaafari… - International journal …, 2018 - Taylor & Francis
Background Exosomes, widely recognized natural nanovesicles, represent one of the
recently discovered modes of intercellular communication due to their ability to transmit …

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

Z Yang, J Xie, J Zhu, C Kang, C Chiang, X Wang… - Journal of Controlled …, 2016 - Elsevier
Exosomes, the smallest subgroup of extracellular vesicles, have been recognized as
extracellular organelles that contain genetic and proteomic information for long distance …

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

H Gomari, M Forouzandeh Moghadam… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Exosomes are small 30–100 nm vesicles secreted by various cell types. They are
released by most cell types, indicating their important role in physiological and pathological …

[HTML][HTML] Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Delivery of miR-381-3p mimic by mesenchymal stem cell-derived exosomes inhibits triple negative breast cancer aggressiveness; an in vitro study

S Shojaei, SM Hashemi, H Ghanbarian… - Stem cell reviews and …, 2021 - Springer
Recent investigations have emphasized the role of aberrant expression of microRNAs
(miRNAs) in progression of almost all types of cancers. Exosomes, membrane-enclosed …

An effective peptide-based platform for efficient exosomal loading and cellular delivery of a microRNA

MD Hade, CN Suire, Z Suo - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Exosomes, membrane-bound nanosized vesicles of biologic origin, are known to contain
various molecules, eg, proteins, lipids, and nucleic acids, which contribute to the exosomes' …