[HTML][HTML] Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential

YL Xiao, Y Gong, YJ Qi, ZM Shao… - Signal Transduction and …, 2024 - nature.com
Diet, serving as a vital source of nutrients, exerts a profound influence on human health and
disease progression. Recently, dietary interventions have emerged as promising adjunctive …

[HTML][HTML] Animal models of diabetic microvascular complications: Relevance to clinical features

R Singh, SA Farooq, A Mannan, TG Singh… - Biomedicine & …, 2022 - Elsevier
Diabetes has become more common in recent years worldwide, and this growth is projected
to continue in the future. The primary concern with diabetes is developing various …

[HTML][HTML] Murine models of obesity

T Martins, C Castro-Ribeiro, S Lemos, T Ferreira… - Obesities, 2022 - mdpi.com
Obesity, classified as an epidemic by the WHO, is a disease that continues to grow
worldwide. Obesity results from abnormal or excessive accumulation of fat and usually leads …

Obesity attenuates inflammation, protein catabolism, dyslipidaemia, and muscle weakness during sepsis, independent of leptin

W Vankrunkelsven, S Derde, J Gunst… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Muscle weakness is a frequently occurring complication of sepsis, associated
with increased morbidity and mortality. Interestingly, obesity attenuates sepsis‐induced …

[HTML][HTML] Development of rat metabolic syndrome models: A review

S Gunawan, A Aulia, V Soetikno - Veterinary world, 2021 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) has become a global problem. With the increasing prevalence
of MetS worldwide, understanding its pathogenesis and treatment modalities are essential …

[HTML][HTML] Synbiotic intervention with an adlay-based prebiotic and probiotics improved diet-induced metabolic disturbance in mice by modulation of the gut microbiota

WC Chiou, BH Chang, HH Tien, YL Cai, YC Fan… - Nutrients, 2021 - mdpi.com
Metabolic syndrome and its associated conditions, such as obesity and type 2 diabetes
mellitus (T2DM), are a major public health issue in modern societies. Dietary interventions …

[HTML][HTML] Neurobiological mechanisms modulating emotionality, cognition and reward-related behaviour in high-fat diet-fed rodents

D Ziemens, C Touma, V Rappeneau - International journal of molecular …, 2022 - mdpi.com
Affective and substance-use disorders are associated with overweight and obesity-related
complications, which are often due to the overconsumption of palatable food. Both high-fat …

[HTML][HTML] Autophagy in hepatic steatosis: a structured review

VM Ramos, AJ Kowaltowski… - Frontiers in cell and …, 2021 - frontiersin.org
Steatosis is the accumulation of neutral lipids in the cytoplasm. In the liver, it is associated
with overeating and a sedentary lifestyle, but may also be a result of xenobiotic toxicity and …

Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets

J Gautam, D Kumari, H Aggarwal, SK Gupta… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Diet-induced obesity mouse models are widely utilized to investigate the underlying
mechanisms of dyslipidemia, glucose intolerance, insulin resistance, hepatic steatosis, and …

Maternal pea fiber supplementation to a high calorie diet in obese pregnancies protects male offspring from metabolic dysfunction in adulthood

GA Andreani, S Mahmood, MS Patel… - … Origins of Health and …, 2023 - cambridge.org
We investigated the influence of maternal yellow-pea fiber supplementation in obese
pregnancies on offspring metabolic health in adulthood. Sixty newly-weaned female …