Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …

Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Cardiac computed tomography (CT) was initially developed as a non-invasive diagnostic
tool to detect and quantify coronary stenosis. Thanks to the rapid technological …

Purpose of review This review article discusses the evolution of extracellular volume (ECV)
quantification using both cardiovascular magnetic resonance (CMR) and computed …

The current era has seen major advances in myocardial imaging. We are now able to
assess cardiac anatomy, function, tissue composition and disease activity across a wide …

Cardiovascular computed tomography (CCT) has undergone rapid maturation over the last
decade and is now of proven clinical utility in the diagnosis and management of coronary …

Background Computed tomography (CT)–derived extracellular volume fraction (ECV) is a
noninvasive method to quantify myocardial fibrosis. Although studies suggest CT is a …

Quantifying myocardial fibrosis (MF) with myocardial extracellular volume measures
acquired during cardiovascular magnetic resonance promises to transform clinical care by …

Please see the Editorial Comment by Fernando Uliana Kay discussing this article.
BACKGROUND. Current methods for calculating the myocardial extracellular volume (ECV) …