Abstract Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease
that is characterized by a high heterogeneity in patients' disease course. Patients with bulbar …

ABSTRACT Introduction: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative
disorder which results in progressive muscle weakness as a prominent feature. However …

Background Magnetic resonance imaging (MRI) of the brain and cervical spinal cord is often
performed in diagnostic evaluation of suspected motor neuron disease/amyotrophic lateral …

Previous neuroimaging studies have revealed that both gray matter (GM) and white matter
(WM) are altered in several morphological aspects in amyotrophic lateral sclerosis (ALS) …

The decline of voluntary bulbar functions such as speech and swallowing are among the
clinical manifestations of amyotrophic lateral sclerosis (ALS) influencing a worst prognosis …

Background & Objective: Despite the great effort spent over recent decades to unravel the
pathological mechanisms underpinning the development of central nervous system …

Background and purpose Amyotrophic lateral sclerosis (ALS) is a rapidly progressing,
phenotypically heterogeneous neurodegenerative disease affecting mainly the motor …

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of upper
and lower motor neurons, with variable involvement of extramotor brain regions. Currently …

Background Patterns of initiation and propagation of disease in Amyotrophic Lateral
Sclerosis (ALS) are still partly unknown. Single or multiple foci of neurodegeneration …

Conflicting findings have been reported regarding the lateralized brain abnormality in
patients with amyotrophic lateral sclerosis (ALS). In this study, we aimed to investigate the …