The longitudinal relaxation time constant (T1) of the myocardium is altered in various
disease states due to increased water content or other changes to the local molecular …

Diffuse interstitial or replacement myocardial fibrosis is a common feature of a broad variety
of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic …

Cardiovascular magnetic resonance (CMR) has taken on an increasingly important role in
the diagnostic evaluation and pre-procedural planning for patients with congenital heart …

Background—Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is
missed by the cardiovascular magnetic resonance (CMR) late gadolinium enhancement …

Background—Extracellular matrix expansion is a key element of ventricular remodeling and
a potential therapeutic target. Cardiovascular magnetic resonance (CMR) T1-mapping …

Background Disturbances in the myocardial extracellular volume fraction (ECV), such as
diffuse or focal myocardial fibrosis or edema, are hallmarks of heart disease. Diffuse ECV …

Background—Cardiac remodeling occurs in response to regular athletic training, and the
degree of remodeling is associated with fitness. Understanding the myocardial structural …

Aim The aim of this study was to determine the value of extracellular volume fraction (ECV)
for the non-invasive assessment of diffuse myocardial fibrosis (MF) in different stages of …

Background—The etiology of ventricular dysfunction in adult congenital heart disease
(ACHD) is not well understood. Diffuse fibrosis is a likely common final pathway and is …

Background Diffuse myocardial fibrosis, and to a lesser extent global myocardial edema, are
important processes in heart disease which are difficult to assess or quantify with …