Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Exercise training is critical for the prevention and treatment of obesity, but its underlying
mechanisms remain incompletely understood given the challenge of profiling …

Background The liver is a key regulator of systemic energy homeostasis and can sense and
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …

In the last decade, clear evidence has emerged that the cellular components of skeletal
muscle are important sites for the release of proteins and peptides called “myokines” …

The 2023 International Olympic Committee (IOC) consensus statement on Relative Energy
Deficiency in Sport (REDs) notes that exposure to low energy availability (LEA) exists on a …

Obesity is a metabolic disease that is caused by a lack of physical activity and is associated
with an increased risk of chronic inflammation. A total of 40 obese adolescent females with …