Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …

The delicate structure of the lung epithelium makes it susceptible to surface tension induced
injury. For example, the cyclic reopening of collapsed and/or fluid-filled airways during the …

Airways of the peripheral lung are prone to closure at low lung volumes. Deficiency or
dysfunction of pulmonary surfactant during various lung diseases compounds this event by …

Acute lung injury (ALI) is an important cause of mortality of patients with sepsis, shock,
trauma, pneumonia, multiple transfusions and pancreatitis. Physalis alkekengi L. var …

Mechanical ventilation can be lifesaving, but> 50% of complications in conditions that
require intensive care are related to ventilatory support, particularly if it is prolonged. We …

This article describes the pathophysiologic basis and clinical role for lung recruitment
maneuvers. It reviews the literature and presents the authors' clinical experience of over 15 …

Lung surfactant is a complex mixture of phospholipids and four surfactant-associated
proteins (SP-A, SP-B, SP-C and SP-D). Its major function in the lung alveolus is to reduce …

Acute respiratory distress syndrome (ARDS) is often characterized by reduced lung
compliance, which suggests dysfunction of the endogenous surfactant system. The …

Increased endothelial permeability and reduction of alveolar liquid clearance capacity are
two leading pathogenic mechanisms of pulmonary edema, which is a major complication of …

There is very little evidence on the value of giving corticoids in cases of seawater drowning
induced acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Therefore, this …