Pulmonary surfactant: A mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Review of current machine perfusion therapeutics for organ preservation
J Xu, JE Buchwald, PN Martins - Transplantation, 2020 - journals.lww.com
Because of the high demand of organs, the usage of marginal grafts has increased. These
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …
The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity
Acute respiratory distress syndrome (ARDS) is undefined in neonates, despite the long-
standing existing formal recognition of ARDS syndrome in later life. We describe the …
standing existing formal recognition of ARDS syndrome in later life. We describe the …
[HTML][HTML] Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation–induced surfactant secretion
GL Chen, JY Li, X Chen, JW Liu… - The Journal of …, 2024 - Am Soc Clin Investig
Pulmonary surfactant is a lipoprotein complex lining the alveolar surface to decrease the
surface tension and facilitate inspiration. Surfactant deficiency is often seen in premature …
surface tension and facilitate inspiration. Surfactant deficiency is often seen in premature …
[HTML][HTML] Surfactant therapy for COVID-19 related ARDS: a retrospective case–control pilot study
Background COVID-19 causes acute respiratory distress syndrome (ARDS) and depletes
the lungs of surfactant, leading to prolonged mechanical ventilation and death. The …
the lungs of surfactant, leading to prolonged mechanical ventilation and death. The …
Engineered PLGA nano-and micro-carriers for pulmonary delivery: challenges and promises
F Ungaro, I d'Angelo, A Miro… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives The aim of this review is to summarize the current state-of-the-art in poly (lactic-co-
glycolic acid)(PLGA) carriers for inhalation. It presents the rational of use, the potential and …
glycolic acid)(PLGA) carriers for inhalation. It presents the rational of use, the potential and …
The POOR Get POORer: a hypothesis for the pathogenesis of ventilator-induced lung injury
DP Gaver III, GF Nieman, LA Gatto… - American journal of …, 2020 - atsjournals.org
Protective ventilation strategies for the injured lung currently revolve around the use of low
Vt, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase …
Vt, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase …
The COVID-19 pandemic: a target for surfactant therapy?
Introduction The dramatic impact of COVID-19 on humans worldwide has initiated an
extraordinary search for effective treatment approaches. One of these is the administration of …
extraordinary search for effective treatment approaches. One of these is the administration of …
Methods and models to investigate the physicochemical functionality of pulmonary surfactant
The pulmonary surfactant (PS) is a complex mixture of lipids and proteins dispersed in the
aqueous lining layer of the alveolar surface. Such a layer plays a key role in maintaining the …
aqueous lining layer of the alveolar surface. Such a layer plays a key role in maintaining the …
[HTML][HTML] The central role of fibrinolytic response in COVID-19—a hematologist's perspective
HC Kwaan, PF Lindholm - International journal of molecular sciences, 2021 - mdpi.com
The novel coronavirus disease (COVID-19) has many characteristics common to those in
two other coronavirus acute respiratory diseases, severe acute respiratory syndrome …
two other coronavirus acute respiratory diseases, severe acute respiratory syndrome …