Vascular adrenoceptors: an update
S Guimarães, D Moura - Pharmacological reviews, 2001 - ASPET
The total and regional peripheral resistance and capacitance of the vascular system is
regulated by the sympathetic nervous system, which influences the vasculature mainly …
regulated by the sympathetic nervous system, which influences the vasculature mainly …
α1‐, α2‐ and β‐adrenoceptors in the urinary bladder, urethra and prostate
MC Michel, W Vrydag - British journal of pharmacology, 2006 - Wiley Online Library
We have systematically reviewed the presence, functional responses and regulation of α1‐,
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …
α1-Adrenoceptor subtypes
H Zhong, KP Minneman - European journal of pharmacology, 1999 - Elsevier
α1-Adrenoceptors are one of three subfamilies of receptors (α1, α2, β) mediating responses
to adrenaline and noradrenaline. Three α1-adrenoceptor subtypes are known (α1A, α1B …
to adrenaline and noradrenaline. Three α1-adrenoceptor subtypes are known (α1A, α1B …
[HTML][HTML] Differential regulation of GPCRs—are GRK expression levels the key?
ESF Matthees, RS Haider, C Hoffmann… - Frontiers in Cell and …, 2021 - frontiersin.org
G protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors and their signal transduction is tightly regulated by GPCR kinases (GRKs) and β …
receptors and their signal transduction is tightly regulated by GPCR kinases (GRKs) and β …
Prostatic α1‐adrenoceptors and uroselectivity
KE Andersson, H Lepor, MG Wyllie - The Prostate, 1997 - Wiley Online Library
BACKGROUND α1‐adrenoceptor antagonists (blockers) are now commonly used in the
treatment of the symptoms of lower urinary tract obstruction. Originally phenoxybenzamine, a …
treatment of the symptoms of lower urinary tract obstruction. Originally phenoxybenzamine, a …
[HTML][HTML] Current Developments on the Role of α1-Adrenergic Receptors in Cognition, Cardioprotection, and Metabolism
DM Perez - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
The α1-adrenergic receptors (ARs) are G-protein coupled receptors that bind the
endogenous catecholamines, norepinephrine, and epinephrine. They play a key role in the …
endogenous catecholamines, norepinephrine, and epinephrine. They play a key role in the …
Pharmacological options in the treatment of benign prostatic hyperplasia
B Kenny, S Ballard, J Blagg, D Fox - Journal of medicinal …, 1997 - ACS Publications
Benign prostatic hyperplasia (BPH) is a common condition which currently accounts for
more than 0.5 million transurethral prostatectomies performed worldwide each year, being …
more than 0.5 million transurethral prostatectomies performed worldwide each year, being …
The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies
JN Pennefather, WAK Lau… - Journal of autonomic …, 2000 - Wiley Online Library
1 We review literature demonstrating (a) the presence and (b) the actions of substances that
mediate or modify neuroeffector transmission to the smooth muscle of the prostrate stroma of …
mediate or modify neuroeffector transmission to the smooth muscle of the prostrate stroma of …
Recent advances in selective α1-adrenoreceptor antagonists as antihypertensive agents
Hypertension is one of the most serious health problems of the modern world with a
continuous rise in the number of patients. Selective α1-adrenoreceptor antagonists though …
continuous rise in the number of patients. Selective α1-adrenoreceptor antagonists though …
Subtype-specific dimerization of α1-adrenoceptors: effects on receptor expression and pharmacological properties
MA Uberti, RA Hall, KP Minneman - Molecular pharmacology, 2003 - ASPET
The potential role of dimerization in controlling the expression and pharmacological
properties of α1-adrenoceptor subtypes was examined using coimmunoprecipitation of …
properties of α1-adrenoceptor subtypes was examined using coimmunoprecipitation of …