Risk stratification based mainly on the impairment of left ventricular ejection fraction has
limited performance in patients with nonischemic dilated cardiomyopathy (NIDCM) …

Lyme carditis is a well-established manifestation of early disseminated Lyme infection, yet
the relationship between late disseminated Lyme disease and the development of dilated …

Aims In response to pro-fibrotic signals, scleraxis regulates cardiac fibroblast activation in
vitro via transcriptional control of key fibrosis genes such as collagen and fibronectin; …

Cardiac fibrosis is a hallmark in late-stage familial dilated cardiomyopathy (DCM) patients,
although the underlying mechanism remains elusive. Cardiac exosomes (Exos) have been …

Aims To characterize the phenotype, clinical outcomes and rate of disease progression in
patients with early‐stage non‐ischaemic cardiomyopathy (early‐NICM). Methods and results …

BACKGROUND: The severity classification of functional mitral regurgitation (FMR) remains
controversial despite adverse prognosis and rapidly evolving interventions. Furthermore, it is …

Heart failure with preserved ejection fraction (HFpEF) is a syndrome defined by the
presence of heart failure symptoms and increased levels of circulating natriuretic peptide …

Objectives: To analyze the association between global myocardial work indices evaluated
by non-invasive left ventricular (LV) pressure-strain loop (PSL) and LV myocardial fibrosis in …

Objective FAP plays a vital role in myocardial injury and fibrosis. Although initially used to
study imaging of primary and metastatic tumors, the use of FAPI tracers has recently been …

Cardiomyopathies are a group of structural and/or functional myocardial disorders which
encompasses hypertrophic, dilated, arrhythmogenic, restrictive, and other cardiomyopathies …