New insights into atypical Alzheimer's disease in the era of biomarkers

J Graff-Radford, KXX Yong, LG Apostolova… - The Lancet …, 2021 - thelancet.com
Most patients with Alzheimer's disease present with amnestic problems; however, a
substantial proportion, over-represented in young-onset cases, have atypical phenotypes …

Alzheimer's disease

JAS Lopez, HM González, GC Léger - Handbook of clinical neurology, 2019 - Elsevier
Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and
functional decline associated with age together with a particular neuropathology. It was first …

Aducanumab: appropriate use recommendations

J Cummings, P Aisen, LG Apostolova, A Atri… - The journal of …, 2021 - Springer
Aducanumab has been approved by the US Food and Drug Administration for treatment of
Alzheimer's disease (AD). Clinicians require guidance on the appropriate use of this new …

Alzheimer disease in African American individuals: increased incidence or not enough data?

LL Barnes - Nature Reviews Neurology, 2022 - nature.com
Research on racial differences in Alzheimer disease (AD) dementia has increased in recent
years. Older African American individuals bear a disproportionate burden of AD and …

Effect of race on prediction of brain amyloidosis by plasma Aβ42/Aβ40, phosphorylated tau, and neurofilament light

SE Schindler, TK Karikari, NJ Ashton, RL Henson… - Neurology, 2022 - AAN Enterprises
Background and Objectives To evaluate whether plasma biomarkers of amyloid
(Aβ42/Aβ40), tau (p-tau181 and p-tau231), and neuroaxonal injury (neurofilament light …

[HTML][HTML] Culture, ethnicity, and level of education in Alzheimer's disease

M Rosselli, IV Uribe, E Ahne, L Shihadeh - Neurotherapeutics, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent cause of dementia, where the abnormal
accumulation of beta-amyloid (Aβ) and tau lead to neurodegeneration as well as loss of …

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

CR Jack Jr, JS Andrews, TG Beach… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The National Institute on Aging and the Alzheimer's Association convened three
separate work groups in 2011 and single work groups in 2012 and 2018 to create …

Racial and ethnic differences in amyloid PET positivity in individuals with mild cognitive impairment or dementia: a secondary analysis of the Imaging Dementia …

CH Wilkins, CC Windon, P Dilworth-Anderson… - JAMA …, 2022 - jamanetwork.com
Importance Racial and ethnic groups with higher rates of clinical Alzheimer disease (AD) are
underrepresented in studies of AD biomarkers, including amyloid positron emission …

Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation

JC Lennon, SL Aita, VAD Bene, T Rhoads… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Although dementia prevalence differs by race, it remains unclear whether
cognition and neuropsychiatric symptom severity differ between Black and White individuals …

Assessment of racial/ethnic disparities in timeliness and comprehensiveness of dementia diagnosis in California

E Tsoy, RE Kiekhofer, EL Guterman, BL Tee… - JAMA …, 2021 - jamanetwork.com
Importance The US aging population is rapidly becoming more racially and ethnically
diverse. Early diagnosis of dementia is a health care priority. Objective To examine the …