Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …

Objectives The lack of systematic evidence on neuroimaging findings in motor neuron
diseases (MND) hampers the diagnostic utility of magnetic resonance imaging (MRI). Thus …

The potential of multiparametric quantitative neuroimaging has been extensively discussed
as a diagnostic tool in amyotrophic lateral sclerosis (ALS). In the past, the integration of …

Objective The study aims at comparing the diagnostic accuracy of qualitative and
quantitative assessment of the susceptibility in the precentral gyrus in detecting amyotrophic …

Objectives: Multiparametric magnetic resonance imaging (MRI) is established as a technical
instrument for the characterisation of patients with amyotrophic lateral sclerosis (ALS). The …

Human aging is characterized by progressive loss of physiological functions. To assess
changes in the brain that occur with increasing age, the concept of brain aging has gained …

Introduction Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurological disease that
leads to progressive motor function degeneration. Diagnosing ALS is challenging due to the …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by motor neuron degeneration. The development of ALS involves metabolite …

Neuroimaging assessment of motor neuron disease has turned into a cornerstone of its
clinical workup. Amyotrophic lateral sclerosis (ALS), as a paradigmatic motor neuron …

Amyotrophic lateral sclerosis (ALS) is the most prevalent type of motor neuron disease
(MND) and is diagnosed with a delay from the first appearance of symptoms. Surrogate …