Pediatric acute lung injury

P Dahlem, WMC Van Aalderen, AP Bos - Paediatric respiratory reviews, 2007 - Elsevier
Among ventilated children, the incidence of acute lung injury (ALI) was 9%; of that latter
group 80% developed the acute respiratory distress syndrome (ARDS). The population …

[HTML][HTML] Overcoming rapid inactivation of lung surfactant: analogies between competitive adsorption and colloid stability

JA Zasadzinski, PC Stenger, I Shieh, P Dhar - Biochimica et Biophysica …, 2010 - Elsevier
Lung surfactant (LS) is a mixture of lipids and proteins that line the alveolar air–liquid
interface, lowering the interfacial tension to levels that make breathing possible. In acute …

Ex vivo reconditioning of marginal donor lungs injured by acid aspiration

I Inci, L Ampollini, S Arni, W Jungraithmayr… - The Journal of heart and …, 2008 - Elsevier
BACKGROUND: Injured lungs due to gastric acid aspiration may be rejected for
transplantation because of the possibility of early graft dysfunction. We hypothesized that …

The use of positive end-expiratory pressure in mechanical ventilation

P Acosta, E Santisbon, J Varon - Critical Care Clinics, 2007 - Elsevier
An improvement in oxygenation for patients who have acute respiratory failure using PEEP
was described close to 40 years ago. Since then, a considerable amount of research has …

Do corticosteroids have a role in preventing or reducing acute toxic lung injury caused by inhalation of chemical agents?

DW de Lange, J Meulenbelt - Clinical Toxicology, 2011 - Taylor & Francis
Objective. To assess the evidence that treatment with corticosteroids improves the outcome
in those exposed to lung-damaging agents. Methods. We searched Pubmed, Toxnet …

Competitive adsorption: a physical model for lung surfactant inactivation

JG Fernsler, JA Zasadzinski - Langmuir, 2009 - ACS Publications
Charged, surface-active serum proteins can severely reduce or eliminate the adsorption of
lung surfactant from the subphase to the alveolar air− liquid interface via a kinetically …

Postperfusion lung syndrome: physiopathology and therapeutic options

SM Yuan - Revista Brasileira de Cirurgia Cardiovascular, 2014 - SciELO Brasil
Postperfusion lung syndrome is rare but can be lethal. The underlying mechanism remains
uncertain but triggering inflammatory cascades have become an accepted etiology. A better …

[HTML][HTML] Non-linear van't Hoff behavior in pulmonary surfactant model membranes

ED Vieira, LGM Basso, AJ Costa-Filho - Biochimica et Biophysica Acta …, 2017 - Elsevier
Pulmonary surfactant exhibits phase coexistence over a wide range of surface pressure and
temperature. Less is known about the effect of temperature on pulmonary surfactant models …

[HTML][HTML] Molecular weight dependence of the depletion attraction and its effects on the competitive adsorption of lung surfactant

PC Stenger, SG Isbell, JA Zasadzinski - Biochimica et Biophysica acta (BBA …, 2008 - Elsevier
Albumin competes with lung surfactant for the air–water interface, resulting in decreased
surfactant adsorption and increased surface tension. Polyethylene glycol (PEG) and other …

Surfactant alterations following donation after cardiac death donor lungs

I Inci, S Arni, C Acevedo, W Jungraithmayr… - Transplant …, 2011 - Wiley Online Library
The use of lungs from donation after cardiac death (DCD) donors is one of the strategies to
increase the donor pool. The aim of this study was to assess the surfactant alterations in …