Neuroimaging in primary lateral sclerosis

EP Pioro, MR Turner, P Bede - Amyotrophic Lateral Sclerosis and …, 2020 - Taylor & Francis
Increased interest in the underlying pathogenesis of primary lateral sclerosis (PLS) and its
relationship to amyotrophic lateral sclerosis (ALS) has corresponded to a growing number of …

Unconventional non-amino acidic PET radiotracers for molecular imaging in gliomas

R Laudicella, N Quartuccio, G Argiroffi, P Alongi… - European Journal of …, 2021 - Springer
Purpose The objective of this review was to explore the potential clinical application of
unconventional non-amino acid PET radiopharmaceuticals in patients with gliomas …

Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis

J Acosta-Cabronero, J Machts, S Schreiber, S Abdulla… - Radiology, 2018 - pubs.rsna.org
Purpose To investigate the whole-brain landscape of iron-related abnormalities in
amyotrophic lateral sclerosis (ALS) by using the in vivo MRI technique of quantitative …

Metabolic spatial connectivity in amyotrophic lateral sclerosis as revealed by independent component analysis

M Pagani, J Öberg, F De Carli, A Calvo… - Human Brain …, 2016 - Wiley Online Library
Objectives Positron emission tomography (PET) and volume of interest (VOI) analysis have
recently shown in amyotrophic lateral sclerosis (ALS) an accuracy of 93% in differentiating …

Prospective validation of 18F-FDG brain PET discriminant analysis methods in the diagnosis of amyotrophic lateral sclerosis

D Van Weehaeghe, J Ceccarini, A Delva… - Journal of Nuclear …, 2016 - Soc Nuclear Med
An objective biomarker for early identification and accurate differential diagnosis of
amyotrophic lateral sclerosis (ALS) is lacking. 18F-FDG PET brain imaging with advanced …

Therapeutic strategies under development targeting inflammatory mechanisms in amyotrophic lateral sclerosis

SG Crisafulli, S Brajkovic, MS Cipolat Mis… - Molecular …, 2018 - Springer
Amyotrophic lateral sclerosis (ALS) is a neurological disease characterized by the
progressive loss of cortical, bulbar, and spinal motor neurons (MNs). The cardinal …

Multicenter validation of [18F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis …

L D'hulst, D Van Weehaeghe, A Chiò… - … Lateral Sclerosis and …, 2018 - Taylor & Francis
Abstract Objective: 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography
(PET) single-center studies using support vector machine (SVM) approach to differentiate …

[HTML][HTML] Longitudinal 18F-FDG PET and MRI reveal evolving imaging pathology that corresponds to disease progression in a patient with ALS-FTD

V Rajagopalan, EP Pioro - Frontiers in neurology, 2019 - frontiersin.org
Single time point positron emission tomography (PET) studies of patients with amyotrophic
lateral sclerosis and frontotemporal dementia (ALS-FTD), have demonstrated …

Brain positron emission tomography in idiopathic normal-pressure hydrocephalus: new 18F-fluorodeoxyglucose pattern in a long-known syndrome

A Cistaro, N Quartuccio, A Piccardo… - Nuclear Medicine …, 2023 - journals.lww.com
Aim Patients with idiopathic normal-pressure hydrocephalus (iNPH) can show a global
reduction in cerebral glucose metabolism at [18 F] Fluorodeoxyglucose (FDG) PET. The …

18F-FDG PET/CT as a molecular biomarker in the diagnosis of amyotrophic lateral sclerosis associated with prostate cancer and progressive supranuclear palsy: A …

EA Cortés Mancera, FA Sinisterra Solis… - Frontiers in Nuclear …, 2023 - frontiersin.org
Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative, multisystem
disorder. Its clinical presentation typically consists of progressive focal muscle atrophy and …