Myxomatous mitral valve degeneration (MMVD) is a leading cause of valve repair or
replacement secondary to the production of mitral regurgitation, cardiac enlargement …

Myxomatous mitral valve disease (MMVD) is the most common heart disease and cause of
cardiac death in domestic dogs. MMVD is characterised by slow progressive myxomatous …

We report a novel label-free quantitative detection of human performance “stress”
biomarkers in different body fluids based on optical absorbance of the biomarkers in the …

In mammals, serotonin (5-HT) levels depend on the availability of tryptophan (TRP). Low 5-
HT concentrations have been linked to behavioural disorders in dogs. This study aimed at …

Background The neurotransmitter serotonin (5‐HT) affects valvular degeneration and dogs
with myxomatous mitral valve disease (MMVD) exhibit alterations in 5‐HT signaling. In …

Abstract Introduction Serotonin (5-hydroxytryptamine [5-HT]) has several biological
functions. In different species, excessive 5-HT has been linked to valvular lesions, similar to …

Background Pathophysiologic mechanisms for the development and progression of
degenerative mitral valve disease (DMVD) remain elusive. Increased concentrations of …

Congestive heart failure (CHF) has been associated with depleted myocardial coenzyme
Q10 (Q10) concentrations in human patients. The aim of this study was to investigate …

Pulmonary venous hypertension (PVH) is caused by deteriorating left ventricular function.
The most common cause of PVH in dogs is myxomatous mitral valve degeneration (MMVD) …

The potential role of serotonin (5-HT) as a marker for identifying sensitivity to clinical
diseases or behavioral disorders and for monitoring treatment emphasizes the need for …