Background Frontotemporal dementias (FTD) include a genetically heterogeneous group of
conditions with distinctive molecular, radiological and clinical features. The majority of …

Background: The cerebellum integrates a multitude of motor and cognitive processes
through ample spinal and supratentorial projections. Despite emerging evidence of adaptive …

Background There is a paucity of cerebral neuroimaging studies in post-polio syndrome
(PPS), despite the severity of neurological and neuropsychological sequelae associated …

Primary lateral sclerosis (PLS) is an adult-onset upper motor neuron disease manifesting in
progressive spasticity and gradually resulting in considerably motor disability. In the …

Abstract Amyotrophic Lateral Sclerosis-Frontotemporal Dementia (ALS-FTD) may present
typical behavioral variant FTD symptoms. This study aims to determine whether profile and …

Amyotrophic lateral sclerosis (ALS) is a deadly neurodegenerative disorder affecting motor
neurons in the spinal cord and brain. Studies have reported on atrophy within segments of …

Background Split phenotypes,(split hand, elbow, leg, and foot), are probably unique to ALS,
and are characterized by having a shared peripheral input of both affected and unaffected …

Neuroimaging assessment of motor neuron disease has turned into a cornerstone of its
clinical workup. Amyotrophic lateral sclerosis (ALS), as a paradigmatic motor neuron …

Our understanding of brain and behavior relationships has expanded exponentially over the
last few decades. This advancement has carried significant ramifications for applied …

The arrival of genotype-specific therapies in amyotrophic lateral sclerosis (ALS) signals the
dawn of precision medicine in motor neuron diseases (MNDs). After decades of academic …