Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Exogenous pulmonary surfactant: A review focused on adjunctive therapy for severe acute respiratory syndrome coronavirus 2 including SP-A and SP-D as added …
Type I and type II pneumocytes are two forms of epithelial cells found lining the alveoli in the
lungs. Type II pneumocytes exclusively secrete 'pulmonary surfactants,'a lipoprotein …
lungs. Type II pneumocytes exclusively secrete 'pulmonary surfactants,'a lipoprotein …
[HTML][HTML] Surfactant therapy for COVID-19 related ARDS: a retrospective case–control pilot study
Background COVID-19 causes acute respiratory distress syndrome (ARDS) and depletes
the lungs of surfactant, leading to prolonged mechanical ventilation and death. The …
the lungs of surfactant, leading to prolonged mechanical ventilation and death. The …
Computational lung modelling in respiratory medicine
Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …
The COVID-19 pandemic: a target for surfactant therapy?
Introduction The dramatic impact of COVID-19 on humans worldwide has initiated an
extraordinary search for effective treatment approaches. One of these is the administration of …
extraordinary search for effective treatment approaches. One of these is the administration of …
Surfactant-mediated wetting and spreading: Recent advances and applications
NM Kovalchuk, MJH Simmons - Current Opinion in Colloid & Interface …, 2021 - Elsevier
Surfactant-mediated wetting and spreading are ubiquitous. Understanding of these
phenomena in-depth allows precise tailoring of wetting performance which can contribute to …
phenomena in-depth allows precise tailoring of wetting performance which can contribute to …
[HTML][HTML] Surfactant therapies for pediatric and neonatal ARDS: ESPNIC expert consensus opinion for future research steps
D De Luca, P Cogo, MC Kneyber, P Biban, MG Semple… - Critical Care, 2021 - Springer
Pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome have
different age-specific characteristics and definitions. Trials on surfactant for ARDS in children …
different age-specific characteristics and definitions. Trials on surfactant for ARDS in children …
[HTML][HTML] Pulmonary surfactant in adult ARDS: current perspectives and future directions
Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory
failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes …
failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes …
Constant Vt Ventilation and Surfactant Dysfunction: An Overlooked Cause of Ventilator-induced Lung Injury
RK Albert - American Journal of Respiratory and Critical Care …, 2022 - atsjournals.org
Ventilator-induced lung injury (VILI) is currently ascribed to volutrauma and/or atelectrauma,
but the effect of constant Vt ventilation (CVtV) has received little attention. This Perspective …
but the effect of constant Vt ventilation (CVtV) has received little attention. This Perspective …
[HTML][HTML] Co-aerosolized pulmonary surfactant and ambroxol for COVID-19 ARDS intervention: what are we waiting for?
P Kumar - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
After more than 225 days of the first reports of the novel coronavirus from China, COVID-19
pandemic is still on surge. The search for an effective and efficient therapeutic and …
pandemic is still on surge. The search for an effective and efficient therapeutic and …