Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

2021 ESC/EACTS Guidelines for the management of valvular heart disease: developed by the Task Force for the management of valvular heart disease of the …

A Vahanian, F Beyersdorf, F Praz… - European heart …, 2022 - academic.oup.com
Health professionals are encouraged to take the ESC/EACTS Guidelines fully into account
when exercising their clinical judgment, as well as in the determination and the …

International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and …

HI Michelena, A Della Corte… - European Journal of …, 2021 - academic.oup.com
Abstract This International Consensus Classification and Nomenclature for the congenital
bicuspid aortic valve condition recognizes 3 types of bicuspid valves: 1. The fused type (right …

Aortic valve replacement versus conservative treatment in asymptomatic severe aortic stenosis: the AVATAR trial

M Banovic, S Putnik, M Penicka, G Doros, MA Deja… - Circulation, 2022 - Am Heart Assoc
Background: Surgical aortic valve replacement (SAVR) represents a class I indication in
symptomatic patients with severe aortic stenosis (AS). However, indications for early SAVR …

Extracellular myocardial volume in patients with aortic stenosis

RJ Everett, TA Treibel, M Fukui, H Lee, M Rigolli… - Journal of the American …, 2020 - jacc.org
Background Myocardial fibrosis is a key mechanism of left ventricular decompensation in
aortic stenosis and can be quantified using cardiovascular magnetic resonance (CMR) …

Imaging and impact of myocardial fibrosis in aortic stenosis

R Bing, JL Cavalcante, RJ Everett, MA Clavel… - JACC: Cardiovascular …, 2019 - jacc.org
Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Cardiac fibrosis in the pressure overloaded left and right ventricle as a therapeutic target

K Schimmel, K Ichimura, S Reddy, F Haddad… - Frontiers in …, 2022 - frontiersin.org
Myocardial fibrosis is a remodeling process of the extracellular matrix (ECM) following
cardiac stress.“Replacement fibrosis” is a term used to describe wound healing in the acute …

2021 ESC/EACTS Guidelines for the management of valvular heart disease: developed by the Task Force for the management of valvular heart disease of the …

F Beyersdorf, A Vahanian, M Milojevic… - European journal of …, 2021 - academic.oup.com
731 F. Beyersdorf and A. Vahanian et al./European Journal of Cardio-Thoracic Surgery
guidelines, which is freely available via the ESC and EACTS website and hosted on the EHJ …

Valvular heart disease: shifting the focus to the myocardium

N Ajmone Marsan, V Delgado, DJ Shah… - European heart …, 2023 - academic.oup.com
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative
valvular heart disease (VHD). However, to give an indication for valvular intervention …

Multi-modality imaging in aortic stenosis: an EACVI clinical consensus document

MR Dweck, K Loganath, R Bing… - European Heart …, 2023 - academic.oup.com
In this EACVI clinical scientific update, we will explore the current use of multi-modality
imaging in the diagnosis, risk stratification, and follow-up of patients with aortic stenosis, with …