Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches

B López, S Ravassa, MU Moreno, GS José… - Nature Reviews …, 2021 - nature.com
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …

[HTML][HTML] T2 mapping in myocardial disease: a comprehensive review

AT O'Brien, KE Gil, J Varghese, OP Simonetti… - Journal of …, 2022 - Elsevier
Cardiovascular magnetic resonance (CMR) is considered the gold standard imaging
modality for myocardial tissue characterization. Elevated transverse relaxation time (T2) is …

Extracellular matrix in heart disease: Focus on circulating collagen type I and III derived peptides as biomarkers of myocardial fibrosis and their potential in the …

A Nikolov, N Popovski - Metabolites, 2022 - mdpi.com
Accumulating evidence indicates that two major proteins are responsible for the structural
coherence of bounding cardiomyocytes. These biomolecules are known as myocardial …

Myocardial fibrosis: why image, how to image and clinical implications

R Bing, MR Dweck - Heart, 2019 - heart.bmj.com
The current era has seen major advances in myocardial imaging. We are now able to
assess cardiac anatomy, function, tissue composition and disease activity across a wide …

Left ventricular global longitudinal strain is associated with long-term outcomes in moderate aortic stenosis

D Zhu, S Ito, WR Miranda, VT Nkomo… - Circulation …, 2020 - Am Heart Assoc
Background: Left ventricular global longitudinal strain (GLS) is associated with long-term
outcomes of patients with severe aortic stenosis. However, its prognostic value in patients …

Diffuse myocardial fibrosis and diastolic function in aortic stenosis

HJ Lee, H Lee, SM Kim, JB Park, EK Kim… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to investigate the relationship between extracellular
volume fraction (ECV), a noninvasive parameter that quantifies the degree of diffuse …

Myocardial tissue characterisation using echocardiographic deformation imaging

MA Moharram, RR Lamberts, G Whalley… - Cardiovascular …, 2019 - Springer
Myocardial pathology results in significant morbidity and mortality, whether due to primary
cardiomyopathic processes or secondary to other conditions such as ischemic heart …

Dual-energy computed tomography in cardiac imaging

B Böttcher, E Zsarnoczay… - Radiologic …, 2023 - radiologic.theclinics.com
Cardiovascular diseases (CVDs) are the leading cause for hospitalization and death
worldwide. 1, 2 Noninvasive imaging plays a major role in treatment and prognosis of CVD …

Myocardial tissue imaging with cardiovascular magnetic resonance

S Nakamori, K Dohi - Journal of Cardiology, 2022 - Elsevier
Alteration in myocardial tissue, such as myocardial fibrosis, edema, inflammation, or
accumulation with amyloid, lipids, or iron, has an important role in the cardiac remodeling …

Clinical utility of strain imaging in assessment of myocardial fibrosis

L Gao, L Zhang, Z Zhang, Y Lin, M Ji, Q He… - Journal of Clinical …, 2023 - mdpi.com
Myocardial fibrosis (MF) is a non-reversible process that occurs following acute or chronic
myocardial damage. MF worsens myocardial deformation, remodels the heart and raises …