[HTML][HTML] Current and future therapies for type 1 diabetes

BJ von Scholten, FF Kreiner, SCL Gough… - Diabetologia, 2021 - Springer
In type 1 diabetes, insulin remains the mature therapeutic cornerstone; yet, the increasing
number of individuals developing type 1 diabetes (predominantly children and adolescents) …

Obesity in people living with type 1 diabetes

B Van der Schueren, D Ellis, RN Faradji… - The Lancet Diabetes & …, 2021 - thelancet.com
Although type 1 diabetes is traditionally considered a disease of lean people, overweight
and obesity are becoming increasingly more common in individuals with type 1 diabetes …

[HTML][HTML] Association of glucagon-like peptide 1 analogs and agonists administered for obesity with weight loss and adverse events: a systematic review and network …

K Vosoughi, J Atieh, L Khanna, K Khoshbin… - …, 2021 - thelancet.com
Background Comparative effectiveness of 7 glucagon-like peptide 1 (GLP-1) agents on
weight loss (WL) in obesity remains unknown. Methods We performed a systematic review …

[HTML][HTML] Effect of glucagon-like peptide-1 receptor agonists on glycemic control, and weight reduction in adults: a multivariate meta-analysis

TL Yeh, MC Tsai, WH Tsai, YK Tu, KL Chien - Plos one, 2023 - journals.plos.org
Aims To explore the effect of glucagon-like peptide-1 receptor agonist (GLP-1 RAs) on
glycemic control and weight reduction in adults. Methods Databases were searched from …

[HTML][HTML] Incretins beyond type 2 diabetes

C Mathieu, I Ahmadzai - Diabetologia, 2023 - Springer
Incretin-based therapies, in particular glucagon-like peptide-1 (GLP-1) receptor agonists,
have been evaluated in other forms of diabetes, but randomised controlled trials are mainly …

Emerging roles of Glucagon like peptide-1 in the management of autoimmune diseases and diabetes-associated comorbidities

S Shao, X Zhang, Q Xu, R Pan, Y Chen - Pharmacology & Therapeutics, 2022 - Elsevier
Currently, gastrointestinal hormone glucagon like peptide-1 (GLP-1) has received significant
attention in maintaining glucose homeostasis through mechanisms involving augmentation …

Glucagon‐like peptide‐1 receptor agonists modestly reduced blood pressure among patients with and without diabetes mellitus: A meta‐analysis and meta …

FB Rivera, GNO Lumbang, DRM Gaid… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim The cardiovascular benefits provided by glucagon‐like peptide‐1 receptor agonists
(GLP‐1RAs) extend beyond weight reduction and glycaemic control. One possible …

[HTML][HTML] Multi-Faceted Influence of Obesity on Type 1 Diabetes in Children–From Disease Pathogenesis to Complications

S Ciężki, E Kurpiewska, A Bossowski… - Frontiers in …, 2022 - frontiersin.org
The prevalence of overweight and obesity among youth patients with diabetes type 1 is
increasing. It is estimated, that even up to 35% of young patients with this type of diabetes …

Glucagon‐like peptide‐1 receptor agonists as adjunctive treatment for type 1 diabetes: Renewed opportunities through tailored approaches?

A Kobayati, A Haidar… - Diabetes, Obesity and …, 2022 - Wiley Online Library
Exogenous insulin has been the mainstay treatment for individuals living with type 1
diabetes (T1D). Although there has been tremendous growth in both pharmacological and …

Glucagon-like peptide 1 analogues as adjunctive therapy for patients with type 1 diabetes: an updated systematic review and meta-analysis

J Park, S Ntelis, E Yunasan, KD Downton… - The Journal of …, 2024 - academic.oup.com
Context Concomitant obesity is common amongst patients with type 1 diabetes mellitus
(T1DM), yet adjunctive therapy options are scarce. Objective We assess the efficacy and …