Spatially resolved mass spectrometry at the single cell: recent innovations in proteomics and metabolomics

MJ Taylor, JK Lukowski… - Journal of the American …, 2021 - ACS Publications
Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

A megatrend challenging analytical chemistry: biosensor and chemosensor concepts ready for the internet of things

M Mayer, AJ Baeumner - Chemical reviews, 2019 - ACS Publications
The Internet of Things (IoT) is a megatrend that cuts across all scientific and engineering
disciplines and establishes an integrating technical evolution to improve production …

[HTML][HTML] MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice

M Aichler, A Walch - Laboratory investigation, 2015 - Elsevier
MALDI Imaging mass spectrometry has entered the field of tissue-based research by
providing unique advantages for analyzing tissue specimen in an unprecedented detail. A …

Mass spectrometry imaging of biomolecular information

B Spengler - Analytical chemistry, 2015 - ACS Publications
Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Ambient mass spectrometry imaging using direct liquid extraction techniques

J Laskin, I Lanekoff - Analytical chemistry, 2016 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful analytical technique that enables label-free
spatial localization and identification of molecules in complex samples. 1− 4 MSI …

Quantification of low molecular weight compounds by MALDI imaging mass spectrometry–A tutorial review

I Rzagalinski, DA Volmer - Biochimica et Biophysica Acta (BBA)-Proteins …, 2017 - Elsevier
Matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI)
permits label-free in situ analysis of chemical compounds directly from the surface of two …

Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization

HM Bergman, E Lundin, M Andersson, I Lanekoff - Analyst, 2016 - pubs.rsc.org
Small molecule neurotransmitters are essential for the function of the nervous system, and
neurotransmitter imbalances are often connected to neurological disorders. The ability to …

Ambient mass spectrometry in metabolomics

CS Clendinen, ME Monge, FM Fernández - Analyst, 2017 - pubs.rsc.org
Since the introduction of desorption electrospray ionization (DESI) mass spectrometry (MS),
ambient MS methods have seen increased use in a variety of fields from health to food …

Organic matrices, ionic liquids, and organic matrices@ nanoparticles assisted laser desorption/ionization mass spectrometry

HN Abdelhamid - TrAC Trends in Analytical Chemistry, 2017 - Elsevier
The applications of organic matrices for matrix assisted laser desorption/ionization mass
spectrometry (MALDI-MS) are reviewed. Recent advances of MALDI-MS using organic …

Multicenter validation study of quantitative imaging mass spectrometry

JA Barry, R Ait-Belkacem, WM Hardesty… - Analytical …, 2019 - ACS Publications
The aim of this study was to assess potential sources of variability in quantitative imaging
mass spectrometry (IMS) across multiple sites, analysts, and instruments. A sample from rat …