[HTML][HTML] NODDI in clinical research
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …
and research investigating the microstructures of nervous tissues, and it has helped us to …
[HTML][HTML] Systematic review: quantitative susceptibility mapping (QSM) of brain iron profile in neurodegenerative diseases
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …
the past decade, development of the new magnetic resonance imaging technique …
CuII(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease
A Southon, K Szostak, KM Acevedo… - British journal of …, 2020 - Wiley Online Library
Background and Purpose Diacetyl‐bis (4‐methyl‐3‐thiosemicarbazonato) copperII (CuII
(atsm)) ameliorates neurodegeneration and delays disease progression in mouse models of …
(atsm)) ameliorates neurodegeneration and delays disease progression in mouse models of …
MRI biomarkers for memory-related impairment in amyotrophic lateral sclerosis: a systematic review
Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …
Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS
NA Goyal, JD Berry, A Windebank, NP Staff… - Muscle & …, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder with
complex biology and significant clinical heterogeneity. Many preclinical and early phase …
complex biology and significant clinical heterogeneity. Many preclinical and early phase …
[HTML][HTML] Tracking a fast-moving disease: longitudinal markers, monitoring, and clinical trial endpoints in ALS
RH Chipika, E Finegan, S Li Hi Shing… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) encompasses a heterogeneous group of phenotypes
with different progression rates, varying degree of extra-motor involvement and divergent …
with different progression rates, varying degree of extra-motor involvement and divergent …
Connectome‐based propagation model in amyotrophic lateral sclerosis
JM Meier, HK van Der Burgh, AD Nitert… - Annals of …, 2020 - Wiley Online Library
Objective Clinical trials in amyotrophic lateral sclerosis (ALS) continue to rely on survival or
functional scales as endpoints, despite the emergence of quantitative biomarkers …
functional scales as endpoints, despite the emergence of quantitative biomarkers …
Focus on the heterogeneity of amyotrophic lateral sclerosis
C Bendotti, V Bonetto, E Pupillo… - … Lateral Sclerosis and …, 2020 - Taylor & Francis
The clinical manifestations of amyotrophic lateral sclerosis (ALS) are variable in terms of age
at disease onset, site of onset, progression of symptoms, motor neuron involvement, and the …
at disease onset, site of onset, progression of symptoms, motor neuron involvement, and the …
Neutrophil-mediated mechanisms of damage and in-vitro protective effect of colchicine in non-vascular Behçet's syndrome
A Bettiol, M Becatti, E Silvestri… - Clinical & …, 2021 - academic.oup.com
Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …
[HTML][HTML] Survival prediction in Amyotrophic lateral sclerosis based on MRI measures and clinical characteristics
C Schuster, O Hardiman, P Bede - BMC neurology, 2017 - Springer
Background Amyotrophic lateral sclerosis (ALS) a highly heterogeneous neurodegenerative
condition. Accurate diagnostic, monitoring and prognostic biomarkers are urgently needed …
condition. Accurate diagnostic, monitoring and prognostic biomarkers are urgently needed …