Acute rheumatic fever and rheumatic heart disease remain major global health problems.
Although strategies for primary and secondary prevention are well established, their …

Context The left atrial appendage (LAA) has been suggested to be the dominant location of
thrombus in atrial fibrillation (AF) and has led to the development of LAA occlusion as a …

Background Antithrombotic therapy in valvular disease is important to mitigate
thromboembolism, but the hemorrhagic risk imposed must be considered. Methods The …

This chapter about antithrombotic therapy for valvular heart disease is part of the American
College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) …

Objectives. We hypothesized an association between atrial thrombi and nonfibrillation atrial
tachyarrhythmias in patients with congenital heart disease. Background. We observed a fatal …

The objective of this study was to prospectively investigate various clinical and
echocardiographic variables to predict the left atrial and left atrial appendage clot and …

Background Recent evidence suggests that regional left atrial coagulation activity may be
increased in mitral stenosis and perhaps contribute to the pathophysiology of left atrial …

We studied 37 consecutive patients with mitral stenosis in sinus rhythm using transthoracic
and transesophageal echocardiography to relate the presence of spontaneous echo …

Thirty-nine patients who had rheumatic mitral valve disease in sinus rhythm were studied to
compare echocardiographic and hemodynamic characteristics between those with and …

Mitral valve stenosis is a common manifestation of chronic rheumatic heart disease. In
rheumatic mitral valve stenosis (RMVS) patients, left atrial spontaneous echo contrast …