The future of cardiovascular computed tomography: advanced analytics and clinical insights

ED Nicol, BL Norgaard, P Blanke, A Ahmadi… - Cardiovascular …, 2019 - jacc.org
Cardiovascular computed tomography (CCT) has undergone rapid maturation over the last
decade and is now of proven clinical utility in the diagnosis and management of coronary …

[HTML][HTML] Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

[HTML][HTML] Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

[HTML][HTML] The impact of left atrium appendage morphology on stroke risk assessment in atrial fibrillation: a computational fluid dynamics study

A Masci, L Barone, L Dedè, M Fedele, C Tomasi… - Frontiers in …, 2019 - frontiersin.org
Atrial fibrillation (AF) carries out a 5-fold increase in stroke risk, related to embolization of
thrombi clotting in left atrium (LA). Left atrial appendage (LAA) is the site with the highest …

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

M Corti, A Zingaro, AM Quarteroni - Computers in Biology and Medicine, 2022 - Elsevier
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

[HTML][HTML] A comprehensive comparison of various patient-specific CFD models of the left atrium for atrial fibrillation patients

J Dueñas-Pamplona, JG García… - Computers in Biology …, 2021 - Elsevier
Background Recently, advances in medical imaging, segmentation techniques, and high-
performance computing have supported the use of patient-specific computational fluid …

[HTML][HTML] In silico Optimization of Left Atrial Appendage Occluder Implantation Using Interactive and Modeling Tools

AM Aguado, AL Olivares, C Yagüe, E Silva… - Frontiers in …, 2019 - frontiersin.org
According to clinical studies, around one third of patients with atrial fibrillation (AF) will suffer
a stroke during their lifetime. Between 70 and 90% of these strokes are caused by thrombus …

[HTML][HTML] Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

J Mill, V Agudelo, AL Olivares, MI Pons, E Silva… - Mathematics, 2021 - mdpi.com
Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …

[HTML][HTML] Pulmonary vein flow split effects in patient-specific simulations of left atrial flow

E Durán, M García-Villalba, P Martínez-Legazpi… - Computers in biology …, 2023 - Elsevier
Disruptions to left atrial (LA) blood flow, such as those caused by atrial fibrillation (AF), can
lead to thrombosis in the left atrial appendage (LAA) and an increased risk of systemic …

Impact of left atrial appendage location on risk of thrombus formation in patients with atrial fibrillation

R Fang, Y Li, Y Zhang, Q Chen, Q Liu, Z Li - Biomechanics and Modeling …, 2021 - Springer
Most strokes in patients with atrial fibrillation (AF) are thought to arise from thrombus
formation in the left atrial appendage (LAA). Assessing the hemodynamics in LAA and left …