The purpose of this article is to review the literature on the side effects of intrathecal and
epidural opioids. English-language articles were identified through a MEDLINE search and …

Morphine is a drug commonly administered via the epidural or intrathecal route, and is
regarded by many as the 'gold-standard'single-dose neuraxial opioid due to its …

The innate immune regulator STING is a critical sensor of self-and pathogen-derived DNA.
DNA sensing by STING leads to the induction of type-I interferons (IFN-I) and other …

Drug Prescribing in Renal Failure: Dosing Guidelines for Adults and Children marks an
important milestone with the publication of this fifth edition. As indicated by its expanded …

The traditional view of opioids held that the individual opioid agonists shared the same
mechanism of action, differing only in their potency and pharmacokinetic properties …

Most children with tumors will require one or more surgical interventions as part of the care
and treatment, including making a diagnosis, obtaining adequate venous access …

The present study evaluated the safety and efficacy of patient-activated delivery of
intrathecal morphine sulfate boluses delivered by way of a novel internalized intrathecal …

Epidural and intrathecal opioid administration has become an important part of
contemporary medical practice in a variety of clinical settings. It has been widely assumed …

Background The ideal perioperative analgesia should provide effective pain relief, avoid the
detrimental effects of the stress response, be simple to administer without the need for …

Long–term use of spinal opioids to treat chronic severe pain is widely established. However,
the indications, shortcomings and complications of the method have not been completely …