Osteoporosis is characterized by low bone mass and microarchitecture deterioration of bone
tissue, leading to enhanced bone fragility and consequent increase in fracture risk. Evidence …

Aging affects the formation of 1, 25-dihydroxyvitamin D (1, 25 [OH] 2D; calcitriol), the active
form of vitamin D. Production of 1, 25 (OH) 2D is reduced by 50% as a result of an age …

Abstract Intracellular 1, 25‐dihydroxyvitamin D receptor (VDR) is expressed in human
skeletal muscle tissue. However, it is unknown whether VDR expression in vivo is related to …

Bone health of the elderly is a major global health concern, since about 1 in 3 women and 1
in 5 men suffer from bone loss and fractures, often called osteoporosis, in old age. Bone …

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BACKGROUND:> Vitamin D deficiency is the most common nutritional deficiency in the
United States. It is seldom measured or recognized, and rarely is treated, particularly in …

The vitamin D receptor (VDR) gene has been implicated as one of the major genetic
components of osteoporosis. We evaluated the relationship between markers of mineral …

Peak bone mass has been shown to be a significant predictor of risk for osteoporosis.
Previous studies have demonstrated that skeletal mass accumulation is under strong …

Background It is assumed that calcium absorption decreases with age, but this is not well
documented. We report a study that addresses this issue. Objective The aim was to establish …

Intestinal calcium absorption decreases with aging, but it is unclear whether this is
attributable to an age-related intestinal resistance to 1, 25-dihydroxyvitamin D [1, 25 (OH) …