Amyotrophic lateral sclerosis is a fatal CNS neurodegenerative disease. Despite intensive
research, current management of amyotrophic lateral sclerosis remains suboptimal from …

Essential tremor (ET) is one of the most common movement disorders, with a reported> 60
million affected individuals worldwide. The definition and underlying pathophysiology of ET …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

The diagnosis of amyotrophic lateral sclerosis can be challenging due to its heterogeneity in
clinical presentation and overlap with other neurological disorders. Diagnosis early in the …

The incidence of neurodegenerative diseases has shown an increasing trend. These
conditions typically cause progressive functional disability. Identification of robust …

There has been an increasing prevalence of neurodegenerative diseases with the rapid
increase in aging societies worldwide. Biomarkers that can be used to detect pathological …

Background Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging
(MRI) technique that can measure the magnetic susceptibility of tissues, which can reflect …

Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …

Emerging studies corroborate the importance of neuroimaging biomarkers and machine
learning to improve diagnostic classification of amyotrophic lateral sclerosis (ALS). While …

Background: With the advances in neuroimaging in amyotrophic lateral sclerosis (ALS), it
has been speculated that multiparametric magnetic resonance imaging (MRI) is capable to …