Pulmonary surfactant: a mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Pharmacological agents for adults with acute respiratory distress syndrome

SR Lewis, MW Pritchard, CM Thomas… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Acute respiratory distress syndrome (ARDS) is a life‐threatening condition
caused by direct or indirect injury to the lungs. Despite improvements in clinical …

[HTML][HTML] Диагностика и интенсивная терапия острого респираторного дистресс-синдрома. Клинические рекомендации Общероссийской общественной …

АИ Ярошецкий, АИ Грицан, СН Авдеев… - Анестезиология и …, 2020 - cyberleninka.ru
Рекомендации Общероссийской общественной организации «Федерация
анестезиологов и реаниматологов» посвящены современному состоянию проблемы …

Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses

AR Tonelli, J Zein, J Adams, JPA Ioannidis - Intensive care medicine, 2014 - Springer
Purpose Multiple interventions have been tested in acute respiratory distress syndrome
(ARDS). We examined the entire agenda of published randomized controlled trials (RCTs) …

[HTML][HTML] An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function

E Da Silva, U Vogel, KS Hougaard, J Pérez-Gil… - Current research in …, 2021 - Elsevier
Inhaled substances, such as consumer products, chemicals at the workplace, and
nanoparticles, can affect the lung function in several ways. In this paper, we explore the …

Severe COVID-19 ARDS treated by bronchoalveolar lavage with diluted exogenous pulmonary surfactant as salvage therapy: In pursuit of the holy grail?

B Ruaro, P Confalonieri, R Pozzan, S Tavano… - Journal of Clinical …, 2022 - mdpi.com
Background: Severe pneumonia caused by coronavirus disease 2019 (COVID-19) is
characterized by inflammatory lung injury, progressive parenchymal stiffening and …

Use of exogenous pulmonary surfactant in acute respiratory distress syndrome (ARDS): Role in SARS-CoV-2-related lung injury

F Cattel, S Giordano, C Bertiond, T Lupia… - Respiratory physiology …, 2021 - Elsevier
Several pre-clinical and clinical trials show that exogenous pulmonary surfactant has clinical
efficacy in inflammatory lung diseases, especially ARDS. By infecting type II alveolar cells …

Clinical review: Exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome-where do we go from here?

A Dushianthan, R Cusack, V Goss, AD Postle… - Critical Care, 2012 - Springer
Acute lung injury and acute respiratory distress syndrome (ARDS) are characterised by
severe hypoxemic respiratory failure and poor lung compliance. Despite advances in clinical …

[HTML][HTML] Synthetic surfactant with a combined SP-B and SP-C analogue is efficient in rabbit models of adult and neonatal respiratory distress syndrome

P Mikolka, N Kronqvist, M Haegerstrand-Björkman… - Translational …, 2023 - Elsevier
Respiratory distress syndrome (RDS) in premature infants is caused by insufficient amounts
of endogenous lung surfactant and is efficiently treated with replacement therapy using …

[HTML][HTML] AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation

SH Choi, AM Wallace, DA Schneider, E Burg, J Kim… - JCI insight, 2018 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) is characterized by an excessive pulmonary
inflammatory response. Removal of excess cholesterol from the plasma membrane of …