Intravenous self-administration preparations, utilizing a chronic indwelling catheter, have
been developed for the rat, rhesus monkey, dog, squirrel monkey, pig, baboon, cat, and …

This study was designed to determine the acute effects of Δ 9-THC on the cortical EEG with
the spectral analysis technique. Adult female Sprague-Dawley rats were implanted with …

The purpose of the study was to define possible self-administration of nalbuphine,
butorphanol and pentazocine by morphine post-addict rats. Rats were prepared with …

The discriminative stimulus effects of l-α-acetylmethadol (LAAM), l-α-acetylnormethadol (nor-
LAAM), l-α-acetyldinormethadol (dinor-LAAM), buprenorphine and methadone were …

We have established procedures to reliably induce opiate dependence in the chick embryo
via in ovo injection, early in embryonic development, of the long-acting and potent opiate N …

Abstract Amphetamine injection (2.5 mg/kg, SC) produced a significant quadratic trend in
mean peak EEG frequencies in the theta band in one group of rats. Progressive increases in …

This study was designed to explore the possible existence of temporal electrophysiological
changes in the central nervous system in dependent rats that were self-administering …

The purpose of the study was to assess possible substitution of either ketocyclazocine or
ethylketocyclazocine for morphine in rats maintaining their own dependence by self …

Abstract Female Sprague-Dawley rats were trained to lever press for food on a variable
interval one minute schedule of reinforcement. Four of these rats were then made tolerant to …

This study characterized discriminative stimulus and other effects of naltrexone in rhesus
monkeys treated daily with the long-acting opioid l-alpha acetylmethadol (LAAM). An initial …