Myocardial fibrosis quantified by extracellular volume is associated with subsequent hospitalization for heart failure, death, or both across the spectrum of ejection …

EB Schelbert, KM Piehler, KM Zareba… - Journal of the …, 2015 - Am Heart Assoc
Background Myocardial fibrosis (MF) in noninfarcted myocardium may be an interstitial
disease pathway that confers vulnerability to hospitalization for heart failure, death, or both …

Cardiovascular magnetic resonance measurement of myocardial extracellular volume in health and disease

DM Sado, AS Flett, SM Banypersad, SK White… - Heart, 2012 - heart.bmj.com
Objective To measure and assess the significance of myocardial extracellular volume (ECV),
determined non-invasively by equilibrium contrast cardiovascular magnetic resonance, as a …

Progression of hypertrophy and myocardial fibrosis in aortic stenosis: a multicenter cardiac magnetic resonance study

RJ Everett, L Tastet, MA Clavel, CWL Chin… - Circulation …, 2018 - Am Heart Assoc
Background: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and
fibrosis. We investigated the natural history of these processes in asymptomatic patients and …

Prognostic significance of LGE by CMR in aortic stenosis patients undergoing valve replacement

G Barone-Rochette, S Piérard… - Journal of the American …, 2014 - jacc.org
Background: Prior studies have shown that late gadolinium enhancement (LGE) by cardiac
magnetic resonance (CMR) can detect focal fibrosis in aortic stenosis (AS), suggesting that it …

Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis

LM Iles, AH Ellims, H Llewellyn, JL Hare… - European Heart …, 2015 - academic.oup.com
Aim Myocardial fibrosis is fundamental in the pathogenesis of heart failure. Late gadolinium
enhancement (LGE) with cardiac magnetic resonance (CMR) imaging is commonly …

Right ventricular fibrosis: A pathophysiological factor in pulmonary hypertension?

S Andersen, JE Nielsen-Kudsk, A Vonk Noordegraaf… - Circulation, 2019 - Am Heart Assoc
The role of right ventricular (RV) fibrosis in pulmonary hypertension (PH) remains a subject
of ongoing discussion. Alterations of the collagen network of the extracellular matrix may …

Athletic cardiac adaptation in males is a consequence of elevated myocyte mass

AK McDiarmid, PP Swoboda, B Erhayiem… - Circulation …, 2016 - Am Heart Assoc
Background—Cardiac remodeling occurs in response to regular athletic training, and the
degree of remodeling is associated with fitness. Understanding the myocardial structural …

T1 mapping for myocardial extracellular volume measurement by CMR: bolus only versus primed infusion technique

SK White, DM Sado, M Fontana, SM Banypersad… - JACC: Cardiovascular …, 2013 - jacc.org
Objectives: The aim of this study was to determine the accuracy of the contrast “bolus only”
T1 mapping cardiac magnetic resonance (CMR) technique for measuring myocardial …

CMR-verified diffuse myocardial fibrosis is associated with diastolic dysfunction in HFpEF

MYM Su, LY Lin, YHE Tseng, CC Chang, CK Wu… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The purpose of this study was to investigate diffuse myocardial fibrosis in
patients with systolic heart failure (SHF) and in patients with heart failure with preserved …

State of the art: clinical applications of cardiac T1 mapping

EB Schelbert, DR Messroghli - Radiology, 2016 - pubs.rsna.org
While cardiovascular magnetic resonance (MR) has become the noninvasive tool of choice
for the assessment of myocardial viability and for the detection of acute myocardial edema …