Diffusion tensor imaging in amyotrophic lateral sclerosis: machine learning for biomarker development

A Behler, HP Müller, AC Ludolph… - International journal of …, 2023 - mdpi.com
Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …

Emerging perspectives of synaptic biomarkers in ALS and FTD

K Krishnamurthy, RK Pradhan - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are debilitating
neurodegenerative diseases with shared pathological features like transactive response …

Disease aggressiveness signatures of amyotrophic lateral sclerosis in white matter tracts revealed by the D50 disease progression model

R Steinbach, N Gaur, A Roediger… - Human brain …, 2021 - Wiley Online Library
Numerous neuroimaging studies in amyotrophic lateral sclerosis (ALS) have reported links
between structural changes and clinical data; however phenotypic and disease course …

Analysis of brain and spinal MRI measures in a common domain to investigate directional neurodegeneration in motor neuron disease

C Toh, A Keslake, T Payne, A Onwuegbuzie… - Journal of …, 2023 - Springer
Background Magnetic resonance imaging (MRI) of the brain and cervical spinal cord is often
performed in diagnostic evaluation of suspected motor neuron disease/amyotrophic lateral …

[HTML][HTML] Longitudinal monitoring of amyotrophic lateral sclerosis by diffusion tensor imaging: Power calculations for group studies

A Behler, D Lulé, AC Ludolph, J Kassubek… - Frontiers in …, 2022 - frontiersin.org
Introduction Diffusion tensor imaging (DTI) can be used to map disease progression in
amyotrophic lateral sclerosis (ALS) and therefore is a promising candidate for a biomarker in …

Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis

AR Alruwaili, K Pannek, RD Henderson, M Gray… - BMC Medical …, 2020 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterized by loss of upper and lower motor neurons. There is a need for an imaging …

[HTML][HTML] Emerging perspectives of synaptic biomarkers in ALS and FTD

K Krishnamurthy, RK Pradhan - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Abstract Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are
debilitating neurodegenerative diseases with shared pathological features like transactive …

Магнитно-резонансная трактография: возможности и ограничения метода, современный подход к обработке данных

АК Никогосова, ТМ Ростовцева… - Медицинская …, 2022 - medvis.vidar.ru
Purpose: systematization of the knowledge about diffusion tensor magnetic resonance
tomography; analysis of literature related to current limitations of this method and …

Magnetic resonance tractogtaphy: possibilities and limitations, modern approach to data processing

AK Nikogosova, TM Rostovtseva, MM Beregov… - Medical …, 2022 - medvis.vidar.ru
Purpose: systematization of the knowledge about diffusion tensor magnetic resonance
tomography; analysis of literature related to current limitations of this method and …

Emerging perspectives of synaptic biomarkers in ALS and FTD

K Krishnamurthy, RK Pradhan - europepmc.org
Abstract Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are
debilitating neurodegenerative diseases with shared pathological features like transactive …