Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …

Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …

Hypertrophic cardiomyopathy (HCM) is a genetic disorder that is characterized by left
ventricular hypertrophy unexplained by secondary causes and a nondilated left ventricle …

Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations
in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR) …

Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Cardiovascular magnetic resonance provides insights into myocardial structure and function
noninvasively, with high diagnostic accuracy and without ionizing radiation. Myocardial …

Background: Myocardial fibrosis is an important pathophysiological mechanism underlying
the development of heart failure (HF). Given the biochemical targets of sacubitril/valsartan …

Myocardial fibrosis, either focal or diffuse, is a common feature of many cardiac diseases
and is associated with a poor prognosis for major adverse cardiovascular events. Although …