The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …

Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Acute lung injury and acute respiratory distress syndrome are clinical entities of multi-
factorial origin frequently seen in traumatically injured patients requiring intensive care. We …

Pulmonary surfactant is a complex of lipids and proteins assembled and secreted by the
alveolar epithelium into the thin layer of fluid coating the respiratory surface of lungs. There …

Twenty years ago, the American-European Consensus Conference on ARDS emphasized
the complexity of the pathogenesis of acute respiratory distress syndrome (ARDS) and …

Introduction The dramatic impact of COVID-19 on humans worldwide has initiated an
extraordinary search for effective treatment approaches. One of these is the administration of …

Amphiphilic block copolymer micelles can mimic the ability of natural lung surfactant to
reduce the air–water interfacial tension close to zero and prevent the Laplace pressure …

Preterm infants are a population at high risk for mortality and adverse health outcomes. With
recent improvements in survival to childhood, increasing attention is being paid to risk of …

Purpose CFD provides a powerful approach to evaluate the deposition of pharmaceutical
aerosols; however, previous studies have not compared CFD results of deposition …

How acute respiratory distress syndrome progresses from underlying disease or trauma is
poorly understood, and there are no generally accepted treatments resulting in a 40 …