[HTML][HTML] Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review
Abstract Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative
disorder characterised by the progressive loss of motor neurons in the brain and spinal cord …
disorder characterised by the progressive loss of motor neurons in the brain and spinal cord …
Frontotemporal pathology in motor neuron disease phenotypes: Insights from neuroimaging
MC McKenna, P Corcia, P Couratier, WF Siah… - Frontiers in …, 2021 - frontiersin.org
Frontotemporal involvement has been extensively investigated in amyotrophic lateral
sclerosis (ALS) but remains relatively poorly characterized in other motor neuron disease …
sclerosis (ALS) but remains relatively poorly characterized in other motor neuron disease …
Predictors of survival in patients with amyotrophic lateral sclerosis: a large meta-analysis
WM Su, YF Cheng, Z Jiang, QQ Duan, TM Yang… - …, 2021 - thelancet.com
Background The survival time of amyotrophic lateral sclerosis (ALS) is greatly variable and
protective or risk effects of the potential survival predictors are controversial. Thus, we aim to …
protective or risk effects of the potential survival predictors are controversial. Thus, we aim to …
Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features
P Bede, A Murad, O Hardiman - Journal of neurology, 2021 - Springer
The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …
academically important, but the practical demands of clinical neurology centre on the …
Phenotypic categorisation of individual subjects with motor neuron disease based on radiological disease burden patterns: a machine-learning approach
Motor neuron disease is an umbrella term encompassing a multitude of clinically
heterogeneous phenotypes. The early and accurate categorisation of patients is hugely …
heterogeneous phenotypes. The early and accurate categorisation of patients is hugely …
Identifying and predicting amyotrophic lateral sclerosis clinical subgroups: a population-based machine-learning study
Background Amyotrophic lateral sclerosis (ALS) is known to represent a collection of
overlapping syndromes. Various classification systems based on empirical observations …
overlapping syndromes. Various classification systems based on empirical observations …
Cost function for low-dimensional manifold topology assessment
In reduced-order modeling, complex systems that exhibit high state-space dimensionality
are described and evolved using a small number of parameters. These parameters can be …
are described and evolved using a small number of parameters. These parameters can be …
Hippocampal metabolic alterations in amyotrophic lateral sclerosis: a magnetic resonance spectroscopy study
F Christidi, GD Argyropoulos, E Karavasilis… - Life, 2023 - mdpi.com
Background: Magnetic resonance spectroscopy (MRS) in amyotrophic lateral sclerosis
(ALS) has been overwhelmingly applied to motor regions to date and our understanding of …
(ALS) has been overwhelmingly applied to motor regions to date and our understanding of …
Brainstem–cortex disconnection in amyotrophic lateral sclerosis: bulbar impairment, genotype associations, asymptomatic changes and biomarker opportunities
Background Bulbar dysfunction is a cardinal feature of ALS with important quality of life and
management implications. The objective of this study is the longitudinal evaluation of a large …
management implications. The objective of this study is the longitudinal evaluation of a large …
[HTML][HTML] Neurometabolic alterations in motor neuron disease: insights from magnetic resonance spectroscopy
F Christidi, E Karavasilis, GD Argyropoulos… - Journal of integrative …, 2022 - imrpress.com
Magnetic resonance spectroscopy (MRS) has contributed important academic insights in
motor neuron diseases (MNDs), particularly in amyotrophic lateral sclerosis (ALS). Over the …
motor neuron diseases (MNDs), particularly in amyotrophic lateral sclerosis (ALS). Over the …