Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive
degeneration of upper motor neurons (UMN) and lower motor neurons (LMN). While LMN …

BACKGROUND AND PURPOSE: Most DTI studies in ALS have been limited to the
assessment of the CST damage. In this study, we used DTI tractography to investigate …

Traumatic brain injury (TBI) has been suggested to increase the risk of amyotrophic lateral
sclerosis (ALS). However, this link remains controversial and as such, here we performed …

BACKGROUND AND PURPOSE: Previous neuropathologic studies in chronic
hydrocephalus have suggested the presence of white matter damage, presumably from …

The structural integrity of the corticospinal tract (CST) after stroke is closely linked to the
degree of motor impairment. Simple and reliable methods of assessing white matter integrity …

Background and purpose: These European Federation of Neurological Societies guidelines
on neuroimaging of motor neuron diseases (MNDs) are designed to provide practical help …

Although the pathogenesis of amyotrophic lateral sclerosis (ALS) is uncertain, there is
mounting neuroimaging evidence to suggest a mechanism involving the degeneration of …

Objective: To test the influence of functional cerebral reorganization in amyotrophic lateral
sclerosis (ALS) on disease progression. Methods: Nineteen predominantly right‐handed …

RATIONALE AND OBJECTIVES: A number of studies have reported decreases in fractional
anistropy (FA) in amyotrophic lateral sclerosis using diffusion tensor imaging (DTI). The …

Brown–Vialetto–van Laere (BVVL) and Fazio–Londe (FL) are rare and clinically overlapping
motor neurons syndromes. Recently BVVL has been associated with mutations in …